Table 4 Association of measures of adiposity with progressive eGFR decline
From: Lipid accumulation product, visceral adiposity index and risk of chronic kidney disease
| Â | Events/N | Proportion | Unadjusted | Model 1 | Model 2 | Model 3 |
|---|---|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |||
VAI | ||||||
 Continuous (per doubling) | 1452/12624 | 12% | 1.23 (1.17, 1.31) | 1.31 (1.23, 1.38) | 1.14 (1.07, 1.21) | 1.11 (1.04, 1.18) |
 Quartiles | ||||||
  ≤ 2.31 | 306/3304 | 9% | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  2.32–3.64 | 355/3275 | 11% | 1.18 (1.00, 1.39) | 1.16 (0.98, 1.38) | 1.02 (0.86, 1.22) | 1.02 (0.86, 1.22) |
  3.65–5.91 | 378/3143 | 12% | 1.37 (1.17, 1.62) | 1.43 (1.22, 1.69) | 1.16 (0.97, 1.37) | 1.14 (0.95, 1.35) |
  ≥ 5.92 | 413/2902 | 14% | 1.62 (1.37, 1.90) | 1.83 (1.55, 2.16) | 1.27 (1.07, 1.51) | 1.20 (1.00, 1.44) |
LAP | ||||||
 Continuous (per doubling) | 1452/12624 | 12% | 1.35 (1.28, 1.43) | 1.42 (1.34, 1.50) | 1.21 (1.14, 1.29) | 1.18 (1.11, 1.26) |
 Quartiles | ||||||
  ≤ 124.89 | 264/3311 | 8% | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  124.9–208.07 | 340/3305 | 10% | 1.29 (1.08, 1.53) | 1.20 (1.01, 1.43) | 1.05 (0.88, 1.25) | 1.06 (0.88, 1.26) |
  208.08–339.57 | 406/3107 | 13% | 1.71 (1.44, 2.02) | 1.65 (1.39, 1.96) | 1.30 (1.09, 1.54) | 1.30 (1.09, 1.56) |
  ≥ 339.58 | 442/2901 | 15% | 2.06 (1.75, 2.44) | 2.25 (1.90, 2.66) | 1.45 (1.22, 1.74) | 1.36 (1.13, 1.63) |
BMI | ||||||
 Continuous (per doubling) | 1452/12624 | 12% | 2.83 (2.32, 3.45) | 3.19 (2.58, 3.95) | 1.89 (1.50, 2.37) | 1.79 (1.42, 2.25) |
 Quartiles | ||||||
  ≤ 25.1 | 238/3042 | 8% | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  25.2–28.3 | 337/3338 | 10% | 1.29 (1.08, 1.55) | 1.29 (1.08, 1.55) | 1.18 (0.98, 1.42) | 1.22 (1.01, 1.47) |
  28.4–32.5 | 389/3271 | 12% | 1.61 (1.36, 1.92) | 1.64 (1.37, 1.95) | 1.32 (1.1.0, 1.59) | 1.33 (1.10, 1.60) |
  > 32.5 | 488/2973 | 16% | 2.29 (1.93, 2.71) | 2.44 (2.05, 2.91) | 1.67 (1.38, 2.01) | 1.63 (1.34, 1.97) |
Waist Circumference | ||||||
 Continuous (per doubling) | 1452/12624 | 12% | 4.22 (3.26, 5.48) | 5.16 (3.91, 6.81) | 2.42 (1.80, 3.25) | 2.21 (1.64, 2.99) |
 Quartiles | ||||||
  ≤ 86.3 | 307/3739 | 8% | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  86.4–95.2 | 298/2936 | 10% | 1.20 (1.01, 1.43) | 1.23 (1.03, 1.48) | 1.07 (0.89, 1.29) | 1.12 (0.93, 1.34) |
  95.3–105.4 | 375/3172 | 12% | 1.44 (1.23, 1.70) | 1.53 (1.29, 1.81) | 1.20 (1.01, 1.43) | 1.20 (1.00, 1.44) |
  > 105.4 | 472/2777 | 17% | 2.27 (1.94, 2.66) | 2.51 (2.13, 2.96) | 1.63 (1.37, 1.95) | 1.58 (1.32, 1.89) |