Table 5 Association of measures of adiposity with incident kidney failure
From: Lipid accumulation product, visceral adiposity index and risk of chronic kidney disease
| Â | Events/N | Incidence rate (%/yr) | Unadjusted | Model 1 | Model 2 | Model 3 |
|---|---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||
VAI | ||||||
 Continuous (per doubling) | 353/27550 | 0.17 | 1.38 (1.25, 1.53) | 1.63 (1.47, 1.81) | 1.33 (1.19, 1.49) | 0.93 (0.82, 1.04) |
 Quartiles | ||||||
  ≤ 2.31 | 56/6873 | 0.11 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  2.32–3.64 | 64/6915 | 0.12 | 1.17 (0.80, 1.70) | 1.27 (0.87, 1.85) | 1.06 (0.73, 1.55) | 0.75 (0.51, 1.10) |
  3.65–5.91 | 111/6886 | 0.22 | 2.01 (1.43, 2.82) | 2.44 (1.74, 3.43) | 1.71 (1.21, 2.41) | 1.02 (0.72, 1.44) |
  ≥ 5.92 | 122/6876 | 0.24 | 2.20 (1.57, 3.07) | 3.42 (2.43, 4.80) | 1.94 (1.37, 2.76) | 0.72 (0.50, 1.03) |
LAP | ||||||
 Continuous (per doubling) | 353/27550 | 0.17 | 1.48 (1.33, 1.64) | 1.67 (1.49, 1.86) | 1.26 (1.12, 1.42) | 0.89 (0.81, 0.99) |
 Quartiles | ||||||
  ≤ 124.89 | 39/6838 | 0.08 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  124.9–208.07 | 74/6943 | 0.14 | 1.74 (1.17, 2.61) | 1.63 (1.09, 2.44) | 1.25 (0.83, 1.87) | 0.99 (0.66, 1.49) |
  208.08–339.57 | 96/6933 | 0.19 | 2.32 (1.58, 3.40) | 2.32 (1.58, 3.40) | 1.49 (1.01, 2.20) | 1.00 (0.67, 1.49) |
  ≥ 339.58 | 144/6836 | 0.29 | 3.48 (2.42, 5.02) | 4.26 (2.95, 6.14) | 2.03 (1.39, 2.97) | 0.82 (0.56, 1.20) |
BMI | ||||||
 Continuous (per doubling) | 353/27550 | 0.17 | 2.50 (1.72, 3.63) | 2.08 (1.40, 3.10) | 0.80 (0.52, 1.23) | 0.55 (0.37, 0.81) |
 Quartiles | ||||||
  ≤ 25.1 | 60/6866 | 0.12 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  25.2–28.3 | 80/6968 | 0.15 | 1.22 (0.86, 1.72) | 1.11 (0.79, 1.57) | 0.86 (0.61, 1.22) | 0.95 (0.67, 1.35) |
  28.4–32.5 | 87/6964 | 0.17 | 1.32 (0.94, 1.85) | 1.13 (0.80, 1.60) | 0.70 (0.50, 1.00) | 0.58 (0.410, 0.84) |
  > 32.5 | 126/6792 | 0.25 | 1.95 (1.42, 2.69) | 1.64 (1.18, 2.28) | 0.76 (0.54, 1.08) | 0.58 (0.40, 0.82) |
Waist Circumference | ||||||
 Continuous (per doubling) | 353/27550 | 0.17 | 5.57 (3.46, 8.97) | 4.27 (2.56, 7.13) | 1.06 (0.62, 1.82) | 0.43 (0.26, 0.70) |
 Quartiles | ||||||
  ≤ 86.3 | 56/7794 | 0.10 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
  86.4–95.2 | 63/6204 | 0.13 | 1.29 (0.89, 1.87) | 1.08 (0.74, 1.57) | 0.82 (0.57, 1.20) | 0.84 (0.58, 1.22) |
  95.3–105.4 | 95/6977 | 0.18 | 1.73 (1.23, 2.43) | 1.43 (1.01, 2.03) | 0.89 (0.63, 1.27) | 0.74 (0.52, 1.05) |
  > 105.4 | 139/6615 | 0.29 | 2.73 (1.98, 3.76) | 2.19 (1.58, 3.04) | 0.99 (0.70, 1.39) | 0.55 (0.39, 0.78) |