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Table 1 Baseline characteristics of the patients

From: Longitudinal trajectory of acidosis and mortality in acute kidney injury requiring continuous renal replacement therapy

Variables

Total

(n = 1815)

1st cluster

(n = 575)

2nd cluster

(n = 748)

3rd cluster

(n = 186)

4th cluster

(n = 188)

5th cluster

(n = 118)

P for trend

Age (years)

64.1 ± 14.9

63.6 ± 15.7

64.0 ± 15.0

63.8 ± 14.9

65.1 ± 14.0

62.0 ± 15.1

0.567

Male (%)

62.8

61.6

61.8

58.6

68.6

72.9*

0.072

Weight (kg)

61.8 ± 13.3

61.6 ± 12.9

61.8 ± 13.0

60.3 ± 12.5

63.3 ± 13.2

66.0 ± 17.1†

0.046

Septic AKI (%)

47

41.7

45.2

58.2‡

54.0*

53.2*

< 0.001

ICU division (%)

0.069

 MICU

51.7

47.8

51.1

58.6‡

57.4†

54.2‡

 SICU

19.1

21.2

19.4

11.8

18.1

19.5

 CPICU

12.7

17.2

14.6

4.3

6.4

1.7

 EICU

16.3

13.2

14.8

24.7

18.1

24.6

 DICU

0.3

0.5

0.1

0.5

0

0

Inotropics use (%)

48.9

49.9

46.8

52.2

48.9

51.7

0.892

Mechanical ventilator (%)

79.4

72.2

80.5‡

86.0‡

85.6‡

88.1‡

< 0.001

Catheter (%)

< 0.001

 Intrajugular

37.6

43.3

36.2*

33.3*

35.1

29.7*

 Femoral

52.2

48.3

53.6

53.8

52.7

59.3

 Others

10.1

8.3

10.2

12.9

12.2

11

Blood flow rate (ml/min)

110.9 ± 24.5

110.0 ± 25.2

111.4 ± 25.6

113.8 ± 25.7

112.7 ± 24.2

110.1 ± 23.8

0.986

Target dose (ml/kg/hr)

42.2 ± 15.2

41.3 ± 15.2

41.3 ± 14.7

43.6 ± 14.4

42.3 ± 13.3

41.8 ± 14.1

0.988

Target UF (ml/d)

0 (0–500)

0 (0–500)

0 (0–1000)

0 (0–500)†

0 (0–500)

0 (0–500)‡

< 0.001

Bicarbonate use (ample/d)

0 (0–4)

0 (0–0)

0 (0–4)‡

4 (0–8)‡

4 (0–8)‡

4 (0–8)‡

< 0.001

Anuria (%)

27.9

23.3

24.9

38.3†

37.6†

35.5*

0.002

CCI score

3.3 ± 2.3

3.2 ± 2.2

3.4 ± 2.3

3.4 ± 2.4

3.5 ± 2.5

3.1 ± 2.3

0.849

SOFA score

11.9 ± 3.7

11.1 ± 3.6

11.9 ± 3.5‡

12.2 ± 3.7‡

13.0 ± 3.1‡

13.2 ± 3.4‡

< 0.001

APACHE II score

26.2 ± 7.8

23.6 ± 6.8

25.5 ± 7.3‡

28.8 ± 8.1‡

29.1 ± 7.0‡

30.9 ± 6.7‡

< 0.001

  1. AKI Acute kidney injury, ICU Intensive care unit, MICU Medical intensive care unit, SICU Surgical intensive care unit, CPICU Cardio-pulmonary intensive care unit, EICU Emergency intensive care unit, DICU Disaster intensive care unit for covid-19 infection, UF Ultrafiltration, CCI Charlson comorbidity index, SOFA Sequential organ failure assessment, APACHE Acute physiologic and chronic health evaluation