Variables | Total (n = 1815) | 1st cluster (n = 575) | 2nd cluster (n = 748) | 3rd cluster (n = 186) | 4th cluster (n = 188) | 5th cluster (n = 118) | P for trend |
---|---|---|---|---|---|---|---|
Age (years) | 64.1 ± 14.9 | 63.6 ± 15.7 | 64.0 ± 15.0 | 63.8 ± 14.9 | 65.1 ± 14.0 | 62.0 ± 15.1 | 0.567 |
Male (%) | 62.8 | 61.6 | 61.8 | 58.6 | 68.6 | 72.9* | 0.072 |
Weight (kg) | 61.8 ± 13.3 | 61.6 ± 12.9 | 61.8 ± 13.0 | 60.3 ± 12.5 | 63.3 ± 13.2 | 66.0 ± 17.1†| 0.046 |
Septic AKI (%) | 47 | 41.7 | 45.2 | 58.2‡ | 54.0* | 53.2* | < 0.001 |
ICU division (%) | 0.069 | ||||||
 MICU | 51.7 | 47.8 | 51.1 | 58.6‡ | 57.4†| 54.2‡ | |
 SICU | 19.1 | 21.2 | 19.4 | 11.8 | 18.1 | 19.5 | |
 CPICU | 12.7 | 17.2 | 14.6 | 4.3 | 6.4 | 1.7 | |
 EICU | 16.3 | 13.2 | 14.8 | 24.7 | 18.1 | 24.6 | |
 DICU | 0.3 | 0.5 | 0.1 | 0.5 | 0 | 0 | |
Inotropics use (%) | 48.9 | 49.9 | 46.8 | 52.2 | 48.9 | 51.7 | 0.892 |
Mechanical ventilator (%) | 79.4 | 72.2 | 80.5‡ | 86.0‡ | 85.6‡ | 88.1‡ | < 0.001 |
Catheter (%) | < 0.001 | ||||||
 Intrajugular | 37.6 | 43.3 | 36.2* | 33.3* | 35.1 | 29.7* | |
 Femoral | 52.2 | 48.3 | 53.6 | 53.8 | 52.7 | 59.3 | |
 Others | 10.1 | 8.3 | 10.2 | 12.9 | 12.2 | 11 | |
Blood flow rate (ml/min) | 110.9 ± 24.5 | 110.0 ± 25.2 | 111.4 ± 25.6 | 113.8 ± 25.7 | 112.7 ± 24.2 | 110.1 ± 23.8 | 0.986 |
Target dose (ml/kg/hr) | 42.2 ± 15.2 | 41.3 ± 15.2 | 41.3 ± 14.7 | 43.6 ± 14.4 | 42.3 ± 13.3 | 41.8 ± 14.1 | 0.988 |
Target UF (ml/d) | 0 (0–500) | 0 (0–500) | 0 (0–1000) | 0 (0–500)†| 0 (0–500) | 0 (0–500)‡ | < 0.001 |
Bicarbonate use (ample/d) | 0 (0–4) | 0 (0–0) | 0 (0–4)‡ | 4 (0–8)‡ | 4 (0–8)‡ | 4 (0–8)‡ | < 0.001 |
Anuria (%) | 27.9 | 23.3 | 24.9 | 38.3†| 37.6†| 35.5* | 0.002 |
CCI score | 3.3 ± 2.3 | 3.2 ± 2.2 | 3.4 ± 2.3 | 3.4 ± 2.4 | 3.5 ± 2.5 | 3.1 ± 2.3 | 0.849 |
SOFA score | 11.9 ± 3.7 | 11.1 ± 3.6 | 11.9 ± 3.5‡ | 12.2 ± 3.7‡ | 13.0 ± 3.1‡ | 13.2 ± 3.4‡ | < 0.001 |
APACHE II score | 26.2 ± 7.8 | 23.6 ± 6.8 | 25.5 ± 7.3‡ | 28.8 ± 8.1‡ | 29.1 ± 7.0‡ | 30.9 ± 6.7‡ | < 0.001 |