Skip to main content

Table 1 Patient characteristics at baseline

From: Clinical impact of suboptimal RAASi therapy following an episode of hyperkalemia

Characteristic

US

Japan

N = 15,488

N = 6020

aExcluded from the denominator for non-missing data

Age at index, years

 Mean (SD)

70.2 (12.4)

76.8 (11.4)

 Median (IQR)

71 (62–80)

78 (71–85)

Male, n (%)

8176 (52.8)

3810 (63.3)

History of HK, n (%)

6064 (39.2)

961 (16.0)

HK severity at index, n (%)

 > 5.0–5.49

4940 (48.6)

207 (32.8)

 5.5–5.99

3414 (33.6)

268 (42.5)

  ≥ 6

1805 (17.8)

156 (24.7)

 Missinga

5329 (34.4)

5389 (89.5)

Diabetes, n (%)

10,236 (66.1)

2550 (42.4)

CKD stage by diagnosis code or by eGFR, n (%)

 3 or 4

11,873 (76.7)

1427 (23.7)

 3

8931 (57.7)

534 (8.9)

 4

2942 (19.0)

893 (14.8)

HF, n (%)

9086 (58.7)

5348 (88.8)

RAASi, n (%)

 ACEi

8886 (57.4)

1281 (21.3)

 ARB

4786 (30.9)

4037 (67.1)

 ARNi

758 (4.9)

38 (0.6)

 MRA

3803 (24.6)

2168 (36.0)

  1. ACEi Angiotensin-converting enzyme inhibitor, ARB Angiotensin receptor blocker, ARNi Angiotensin receptor-neprilysin inhibitor, CKD Chronic kidney disease, eGFR Estimated glomerular filtration rate, HF Heart failure, HK Hyperkalemia, IQR Interquartile range, MRA Mineralocorticoid receptor antagonist, RAASi Renin-angiotensin-aldosterone system inhibitor, SD Standard deviation