Table 1 Baseline characteristics of the patients
Nafamostat mesylate (n = 129) | Unfractionated heparin (n = 157) | p-value | |
|---|---|---|---|
Age, years | 68 (12) | 68 (13) | 0.737 |
Sex | 0.271 | ||
Male, n (%) | 92 (71) | 122 (78) | |
Female, n (%) | 37 (29) | 35 (22) | |
Height, cm | 162.0 (10.2) | 163.6 (8.9) | 0.176 |
Weight, kg | 59.6 (19.1) | 60.5 (13.2) | 0.639 |
Admission type, n (%) | < 0.001 | ||
Medical | 85 (65.9) | 69 (43.9) | |
Emergency surgery | 26 (20.2) | 24 (15.3) | |
Elective surgery | 18 (14.0) | 64 (40.8) | |
Cardiovascular surgery, n (%) | 47 (36.4) | 98 (62.4) | < 0.001 |
Admission route, n (%) | < 0.001 | ||
Ward | 63 (48.8) | 38 (24.2) | |
Operation room | 39 (30.2) | 81 (51.6) | |
Emergency room | 26 (20.2) | 34 (21.7) | |
Other hospital | 1 (0.8) | 4 (2.5) | |
APACHE II score | 28 (7) | 27 (7) | 0.061 |
Chronic medical condition | |||
Hypertension, n (%) | 99 (76.7) | 134 (85.4) | 0.087 |
Ischemic heart disease, n (%) | 43 (33.3) | 80 (51.0) | 0.004 |
Diabetes mellitus, n (%) | 18 (14.0) | 19 (12.1) | 0.774 |
Maintenance dialysis, n (%) | 56 (43.4) | 102 (65.0) | < 0.001 |
Heart failure, n (%) | 3 (2.3) | 2 (1.3) | 0.824 |
Respiratory failure, n (%) | 2 (1.6) | 3 (1.9) | 1.000 |
Liver failure, n (%) | 2 (1.6) | 0 (0.0) | 0.394 |
Liver cirrhosis, n (%) | 9 (7.0) | 2 (1.3) | 0.029 |
Bleeding risk, n (%) | 56 (43.4) | 82 (52.2) | 0.172 |