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Table 2 Laboratory data at the start of CKRT and at 24 h

From: Unfractionated heparin versus nafamostat mesylate for anticoagulation during continuous kidney replacement therapy: an observational study

 

Baseline

24 h

Nafamostat mesylate (n = 129)

Unfractionated heparin (n = 157)

p-value

Nafamostat mesylate (n = 129)

Unfractionated heparin (n = 157)

p-value

Total bilirubin, mg/dL

2.2 (4.5)

1.7 (4.4)

0.432

2.4 (4.6)

2.0 (4.9)

0.499

Albumin, g/dl

2.5 (0.6)

2.6 (0.6)

0.233

2.3 (0.5)

2.4 (0.5)

0.032

Uric acid, mg/dL

6.1 (3.1)

6.00(2.8)

0.724

4.7 (2.2)

4.6 (2.1)

0.528

Blood urea nitrogen, mg/dL

58 (34)

56 (28)

0.458

53 (30)

49 (21)

0.230

Serum creatinine, mg/dL

4.92 (3.48)

5.60 (3.44)

0.102

3.97 (2.50)

4.59 (2.57)

0.041

Estimated GFR, ml/min/1.73m2

18.1 (18.9)

17.1 (21.8)

0.688

19.2 (17.1)

18.1 (22.6)

0.648

Ca, mg/dL

7.9 (1.2)

8.1 (0.9)

0.146

8.2 (0.8)

8.3 (0.8)

0.304

Mg, mg/dL

2.3 (0.7)

2.3 (0.6)

0.716

2.3 (0.5)

2.2 (0.4)

0.345

IP, mg/dL

5.2 (2.2)

4.9 (2.0)

0.208

4.5 (1.6)

4.2 (1.6)

0.155

Hemoglobin, g/dL

9.7 (2.2)

10.1 (1.9)

0.109

9.1 (1.8)

9.3 (1.6)

0.253

Platelet, × 103/μl

153.3 (98.6)

153.3 (79.6)

0.996

120.0 (83.2)

128.3 (76.5)

0.383

PT-INR > 1.5, n, (%)

12 (9.3)

18 (11.5)

0.689

12 (9.3)

17 (10.8)

0.819

APTT, sec

  

0.300

  

0.088

 < 40, n (%)

92 (71.3)

101 (64.3)

 

58 (45.0)

61 (38.9)

 

 40 – 80, n (%)

36 (27.9)

52 (33.1)

 

60 (46.5)

90 (57.3)

 

  > 80, n (%)

1 (0.8)

4 (2.5)

 

11 (8.5)

6 (3.8)

 
  1. Values are presented as means with standard deviations, otherwise specified
  2. GFR glomerular filtration rate, PT-INR prothrombin time-international normalised ratio, APTT activated partial thromboplastin time