Table 3 Secondary outcomes before and after propensity score matching
Before propensity score matching | After propensity score matching | ||||
|---|---|---|---|---|---|
Nafamostat mesylate (n = 129) | Unfractionated heparin (n = 157) | Nafamostat mesylate (n = 91) | Unfractionated heparin (n = 91) | p-value | |
ICU mortality, n (%) | 33 (25.6) | 21 (13.4) | 24 (26.4) | 14 (15.4) | 0.101 |
Hospital mortality, n (%) | 52 (40.3) | 42 (26.8) | 36 (39.6) | 29 (31.9) | 0.353 |
ICU length of stay, day | 11.0 (15.3) | 8.4 (12.2) | 12.4 (17.3) | 9.5 (13.0) | 0.193 |
Hospital length of stay, day | 73.8 (69.9) | 75.5 (89.8) | 78.8 (74.8) | 77.4 (71.8) | 0.895 |
Mechanical ventilation days, day | 5.7 (12.6) | 4.1 (11.3) | 6.5 (14.3) | 4.6 (11.9) | 0.342 |
Transfusion within 48 h of CKRT | |||||
Red blood cells (ml) | 122 (242) | 92 (230) | 112(238) | 112 (238) | 0.729 |
Platelet concentrate(ml) | 26 (95) | 20 (69) | 30 (104) | 18 (68) | 0.352 |
Fresh frozen plasma (ml) | 82 (371) | 18 (120) | 108 (432) | 24 (120) | 0.072 |
C-reactive protein at 24 h, mg/dL | 12 (10) | 13 (10) | 12.71 (10.51) | 12.96 (10.21) | 0.873 |
White blood cell at 24 h, × 102/μL | 0.155 | ||||
< 40, n (%) | 5 (3.9) | 2 (1.3) | 5 (5.5) | 2 (2.2) | |
40 – 90, n (%) | 34 (26.4) | 66 (42.0) | 27 (29.7) | 38 (41.8) | |
90 < , n (%) | 90 (69.8) | 89 (56.7) | 59 (64.8) | 51 (56.0) | |
Dialysis dependence at dischargea, n (%) | 50/77 (64.9) | 99/115 (86.1) | 40/55 (72.7) | 51/62 (82.3) | 0.310 |
Creatinine at dischargeb, mg/dL | 1.70 (1.08) | 1.63 (1.04) | 2.06 (1.08) | 1.31 (0.74) | 0.061 |