Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury

Table 2 Factors related to all-cause mortality

Variables	Hazard ratio (95% CI)	P
Age (per 1 year)	1.006 (0.999–1.012)	0.099
Female (vs. male)	0.970 (0.861–1.093)	0.970
Body weight (per 1 kg)	0.998 (0.994–1.003)	0.431
Septic AKI (vs. non-septic AKI)	1.337 (1.187–1.506)	< 0.001
Target dose (per 10 ml/kg/hr)	1.020 (0.977–1.065)	0.368
Blood flow rate (per 10 ml/min)	1.013 (0.990–1.037)	0.278
Target ultrafiltration (per 1 L/day)	1.008 (0.932–1.090)	0.884
Mechanical ventilation (vs. none)	1.493 (1.288–1.730)	< 0.001
≥ 3 vasopressors (vs. < 3)	1.593 (1.382–1.837)	< 0.001
SOFA score (per 1 score)	1.132 (1.113–1.151)	< 0.001
APACHE II score (per 1 score)	1.055 (1.047–1.063)	< 0.001
CCI score (per 1 score)	1.014 (1.013–1.066)	< 0.001

CI confidence interval, AKI acute kidney injury, SOFA Sequential Organ Failure Assessment, APACHE Acute Physiology and Chronic Health Evaluation, CCI Charlson Comorbidity Index

ISSN: 1471-2369