Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury

Table 3 Risk of mortality according to lactate levels

Outcomes	Lactate levels	Unadjusted OR (95% CI)	P	Adjusted OR (95% CI)^a	P
In-hospital mortality	Low	1 (Reference)		1 (Reference)
	Moderate	2.29 (1.744–3.009)	< 0.001	1.64 (1.222–2.207)	0.001
	High	6.99 (5.137–9.515)	< 0.001	4.18 (2.985–5.847)	< 0.001
ICU mortality	Low	1 (Reference)		1 (Reference)
	Moderate	2.25 (1.707–2.961)	< 0.001	1.55 (1.154–2.093)	0.004
	High	7.38 (5.474–9.942)	< 0.001	4.22 (3.048–5.830)	< 0.001
CRRT mortality	Low	1 (Reference)		1 (Reference)
	Moderate	2.11 (1.596–2.798)	< 0.001	1.48 (1.099–2.004)	0.010
	High	7.45 (5.567–10.102)	< 0.001	4.45 (3.231–6.135)	< 0.001

Low, ≤ 2 mmol/l; moderate, 2.1–7.5 mmol/l; high, ≥ 7.6 mmol/l
OR odds ratio, CI confidence interval, ICU intensive care unit, CRRT continuous renal replacement therapy
^aAdjusted for age, sex, body weight, septic acute kidney injury, mechanical ventilation, vasopressors, and scores of SOFA, APACHE II, and CCI

ISSN: 1471-2369