Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury

Table 4 Risk of mortality according to lactate clearance

Outcomes	Lactate clearance	Unadjusted OR (95% CI)	P	Adjusted OR (95% CI)^a	P
In-hospital mortality	Less clearance	1 (Reference)		1 (Reference)
In-hospital mortality	Well clearance	0.51 (0.396–0.664)	< 0.001	0.51 (0.382–0.668)	< 0.001
ICU mortality	Less clearance	1 (Reference)		1 (Reference)
ICU mortality	Well clearance	0.44 (0.343–0.560)	< 0.001	0.42 (0.317–0.544)	< 0.001
CRRT mortality	Less clearance	1 (Reference)		1 (Reference)
CRRT mortality	Well clearance	0.43 (0.340–0.551)	< 0.001	0.41 (0.315–0.533)	< 0.001

Well clearance, > 0%; less clearance, ≤ 0%
OR odds ratio, CI confidence interval, ICU intensive care unit, CRRT continuous renal replacement therapy
^aAdjusted for age, sex, body weight, septic acute kidney injury, mechanical ventilation, vasopressors, and scores of SOFA, APACHE II, and CCI

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