Table 2 Univariate and multivariate logistic regression for severe PCP
Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|
Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
Age | 1.06 (1.01–1.11) | 0.012 | 1.07 (1.01–1.13) | 0.027 |
Sex | 1.04 (0.34–3.19) | 0.945 | ||
Time from onset of symptom to hospital admission | 0.90 (0.80–1.01) | 0.067 | ||
Time from transplantation to PCP | 0.97 (0.92–1.01) | 0.114 | 0.92 (0.86–0.99) | 0.024 |
Time from discontinuation of TMP/SMX to PCP | 0.91 (0.79–1.05) | 0.202 | ||
HLA-A, B, DR mismatch | 1.68 (1.08–2.62) | 0.022 | ||
Immunosuppressant Tacrolimus Cyclosporin | 1.04 (0.31–3.49) 0.96 (0.29–3.24) | 0.951 0.951 | ||
CMV co-infection | 1.57 (0.49–5.08) | 0.451 | ||
BKV co-infection | 1.36 (0.33–5.55) | 0.671 | ||
Use of rituximab | 2.63 (0.79–8.72) | 0.114 | ||
Lymphopenia (TLC < 1,000 mm3) | 3.70 (0.96–14.29) | 0.058 | 6.48 (1.05–40.09) | 0.044 |
History of acute rejection treatment within 1 year | 2.63 (0.79–8.72) | 0.114 | 8.28 (1.29–53.20) | 0.026 |