Table 2 Baseline Demographic and Clinical Characteristics of Pediatric NEPTUNE Participants by Tobacco Exposure Groups
From: Tobacco exposure in adults and children with proteinuric glomerulopathies: a NEPTUNE cohort study
N (%) or Mean±SD N = 188a | Non-smoker N = 156 | Exclusive Passive smoker N = 32 | p-value |
|---|---|---|---|
Age | 10.1±4.91 | 8.0±4.9 | 0.04 |
Sex: Male | 88 (56.4%) | 19 (59.4%) | 0.84 |
Black Race | 60 (39.5%) | 11 (39.5%) | 0.69 |
Drug use | 0 (0.0%) | 0 (0.0%) | >0.99 |
Alcohol use: None | 134 (97.8%) | 30 (93.8%) | 0.05 |
Daily | 0 (0.0%) | 1 (3.1%) | Â |
3-4 times a week | 0 (0.0%) | 0 (0.0%) | Â |
1-2 times a week | 1 (0.7%) | 0 (0.0%) | Â |
1-2 times a month | 2 (1.5%) | 0 (0.0%) | Â |
< once a month | 0 (0.0%) | 1 (3.1%) | Â |
English as primary language | 138 (88.5%) | 30 (96.8%) | 0.21 |
Maternal Education Level: | Â | Â | 0.01 |
High School diploma | 24 (15.4%) | 7 (21.9%) | Â |
2-year Associates degree/certificate | 42 (26.9%) | 4 (12.5%) | Â |
4-year College degree | 27 (17.3%) | 4 (12.5%) | Â |
Master level diploma | 8 (5.1%) | 0 (0.0%) | Â |
Graduate level diploma | 7 (4.5%) | 0 (0.0%) | Â |
Not available | 4 (2.6%) | 1 (3.1%) | Â |
Unknown | 5 (3.2%) | 1 (3.1%) | Â |
BMI (kg/m2) | 22.3±6.7 | 21.8±7.0 | 0.3 |
BMI percentile | 76.6±28.2 | 82.2±25.3 | 0.16 |
Obesity | 49 (0.3) | 17 (53.1) | 0.12 |
Birth weight (g) | 4610.0±7316.6 | 3501.2±260.3 | 0.27 |
Cohort: MN | 1 (0.6%) | 0 (0.0%) | 0.76 |
MCD | 80 (51.6%) | 19 (59.4%) | Â |
Other | 27 (17.4%) | 6 (18.8%) | Â |
FSGS | 47 (30.3%) | 7 (21.9%) | Â |
Blood Pressure Status: Normal | 72 (48.6%) | 13 (43.3%) | 0.87 |
Elevated BP | 14 (9.5%) | 3 (10.0%) | Â |
Hypertensive BP | 62 (41.9%) | 14 (46.7%) | Â |
SBP (mmHg) | 111.43±15.403 | 106.70±18.904 | 0.12 |
SBP Index | 0.9425±0.11553 | 0.9418±0.08770 | 0.79 |
DBP (mmHg) | 76.3±11.4 | 72.9±10.2 | 0.04 |
DBP index | 0.9±0.56 | 0.94±0.18 | 0.41 |
eGFR (ml/min/1.73m2) | 99.2±33.3 | 121.2±68.4 | 0.06 |
UPC ratio (g/g) | 3.23±6.2 | 3.6 ±3.9 | 0.80 |
Edema present | 55 (36.7%) | 16 (50.0%) | 0.17 |
Albumin (mg/dl) | 3.2±1.0 | 2.9±1.2 | 0.26 |
Total Cholesterol (mg/dL) | 295.3±136.3 | 316.8±145.7 | 0.41 |
HDL (mg/dL) | 77.0±28.1 | 82.2±30.9 | 0.32 |
LDL (mg/dL) | 179.4±108.4 | 197.3±115.8 | 0.4 |
Triglycerides (mg/dL) | 194.4±155.4 | 186.5±167.7 | 0.69 |
Steroid use | 90 (46.7%) | 19 (59.4%) | >0.99 |
CNI use | 30 (19.2%) | 8 (25.0%) | 0.67 |
RAAS blocker use | 50 (32.1%) | 9 (28.1%) | 0.57 |
Arterial Hyalinosis | 0.01±0.07 | 0.05±0.23 | 0.36 |
Arteriosclerosis (%) | 0.06±0.21 | 0.08±0.25 | 0.69 |