Table 3 Outcomes among NEPTUNE Participants by Tobacco Exposure Groups

N (%)

N = 371

Non-smoker

N = 191

Active smoker

N = 54

Former smoker

N = 108

Exclusive Passive smoker

N = 18

Non-smoker

N = 156

Exclusive Passive smoker

N = 32

Cardiovascular Disease Risk Factors

Self-reported Hypertension at Baseline

115 (60.2%)

32 (59.3%)

67 (62%)

13 (72.2%)

34 (21.8%)

10 (31.2%)

Self-reported Hypertension after Baseline

5 (2.6%)

1 (1.9%)

2 (1.9)

0 (0%)

5 (3.2%)

4 (12.5%)

Cardiovascular Disease Events

Coronary Heart Disease at Baseline

13 (6.8%)

5 (9.3%)

5 (4.6%)

0 (0%)

0 (0%)

0 (0%)

Coronary Heart Disease after Baseline

1 (0.5%)

1 (1.9%)

1 (0.93%)

0 (0%)

0 (0%)

0 (0%)

Heart Failure at Baseline

5 (2.6%)

3 (5.6%)

1 (0.93%)

0 (0%)

0 (0%)

0 (0%)

Heart Failure after Baseline

4 (2.1%)

0 (0%)

1 (0.93%)

0 (0%)

1 (0.64%)

0 (0%)

Stroke at Baseline

3 (1.6%)

4 (7.4%)

5 (4.6%)

1 (5.6%)

0 (0%)

0 (0%)

Stroke after Baseline

1 (0.5%)

1 (1.9%)

2 (1.9%)

0 (0%)

0 (0%)

0 (0%)

Peripheral Vascular Disease at Baseline

2 1%)

2 (3%)

2 (1.9%)

0 (0%)

0 (0%)

0 (0%)

Peripheral Vascular Disease after Baseline

2 (1%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

Kidney Disease Outcomes

Complete Remission

98 (51.3)

23 (42.6)

59 (54.6)

6 (50%)

111 (71.2%)

23 (71.9%)

Chronic Kidney Disease Progression*

39 (20.4)

13 (24.1)

26 (24.1)

4 (22.2%)

31 (19.9%)

4 (12.5%)

Kidney Failure

16 (8.4)

4 (7.4)

8 (7.4)

2 (11.1%)

1 (0.64%)

0 (0%)

Co-Morbid Diagnoses

Cancer at Baseline

15 (7.9%)

5 (9.3%)

5 (4.6%)

1 (5.6%)

0 (0%)

0 (0%)

Cancer after Baseline

4 (2.1%)

2 (3.7%)

3 (2.8%)

1 (5.6%)

1 (0.64%)

0 (0%)

Thromboemboilic Events at Baseline**

6 (3.1%)

1 (1.9%)

10 (9.3%)

0 (0%)

4 (2.6%)

0 (0%)

Thromboembolic Events after Baseline

6 (3.1%)

1 (1.9%)

4 (3.7%)

0 (0%)

1 (0.64%)

0 (0%)