Table 4 Association between Tobacco Exposure and Cardiovascular Risk Factors and Kidney-related Outcomes in Adjusted Regression Models (reference group: non-smokers)a in Adult NEPTUNE Participants
From: Tobacco exposure in adults and children with proteinuric glomerulopathies: a NEPTUNE cohort study
| Â | Active Smokers | Exclusive Passive Smokers | |||
|---|---|---|---|---|---|
| Â | OR (95% CI) | p value | OR (95% CI) | p value | |
Hypertensive BP | 0.51 (0.22, 1.16) | 0.11 | 1.26 (0.84, 1.90) | 0.26 | |
Dyslipidemia | 1.29 (0.78, 2.13) | 0.32 | Failed to Converge | Â | |
Complete remission | 0.86 (0.70, 1.05) | 0.13 | 1.00 (0.79, 1.27) | 0.98 | |
|  | β (95% CI) | p value | β (95% CI) | p value | |
Systolic BP (mmHg) | 1.26 (-1.21, 3.72) | 0.32 | 0.363 (-1.88, 2.61) | 0.75 | |
Diastolic BP (mmHg) | 0.43 (-2.05, 2.91) | 0.73 | 0.01 (-2.00, 2.01) | 0.99 | |
HDL (mg/dl) | 0.00 (-3.75, 3.75) | 1 | 1.34 (-6.04, 8.71) | 0.72 | |
LDL (mg/dl) | 7.12 (-4.01, 18.24) | 0.21 | -6.79 (-29.78, 16.21) | 0.56 | |
Triglycerides (mg/dl) | 3.41 (-31.02, 37.84) | 0.58 | -21.86 (-59.13, 15.40) | 0.25 | |
Total Cholesterol (mg/dl) | 17.91 (0.06, 35.76) | 0.049 | -38.85 (-87.21, 9.51) | 0.12 | |
UPCr (g/g) | 0.39 (-0.09, 0.87) | 0.12 | 1.23 (0.13, 2.33) | 0.03 | |
eGFR (ml/min/1.73m2) | 3.06 (-2.96, 9.07) | 0.32 | 4.13 (-2.52, 10.78) | 0.22 | |
| Â | Â h (95% CI) | p value | HR (95% CI) | p value | |
CKD progression | 1.24 (0.91, 1.68) | 0.17 | 0.71 (0.48, 1.04) | 0.08 | |
Kidney failure | 0.82 (0.51, 1.32) | 0.41 | - | - | |