Table 3 Summary table of differences in kidney function, kidney damage and blood pressure by foetal kidney volume: univariable and multivariable*
From: Role of foetal kidney size on kidney function in childhood: the born in bradford cohort renal study
Model variable | Schwartz eGFR creatinine only | Schwartz eGFR combined | Zappitelli eGFR cystatin C only | Filler eGFR cystatin C only | Cystatin C | Albumin creatinine ratio | Protein creatinine ratio (logged) | Systolic blood pressure (sBP) | Diastolic blood pressure (dBP) | |
|---|---|---|---|---|---|---|---|---|---|---|
Detectable | Result | |||||||||
| Â | Beta estimate (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) | Odds ratio (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) | Beta estimate (95% CI) |
Unadjusted – n | 380 | 361 | 426 | 426 | 426 | 416 | 211 | 392 | 603 | 603 |
Renal Volume, cm3 | 0.56 -0.05 to 1.17 | 0.61 0.29 to 0.93 | 0.60 0.25 to 0.95 | 2.12 0.89 to 3.36 | -0.005 -0.007 to -0.002 | 1.04 0.98 to 1.12 | 0.05 -0.05 to 0.15 | -0.01 -0.02 to 0.004 | 0.004 -0.33 to 0.34 | -0.02 -0.29 to 0.25 |
Ethnicity - n | 380 | 361 | 426 | 426 | 426 | 416 | 211 | 392 | 603 | 603 |
Renal Volume, cm3 | 0.72 0.08 to 1.36 | 0.72 0.38 to 1.05 | 0.53 0.17 to 0.90 | 1.89 0.61 to 3.17 | -0.004 -0.007 to -0.001 | 1.05 0.98 to 1.13 | 0.07 -0.03 to 0.17 | -0.01 -0.02 to 0.004 | 0.13 -0.21 to 0.47 | 0.11 -0.16 to 0.38 |
Socio-demographic - n | 380 | 361 | 426 | 426 | 426 | 416 | 211 | 392 | 603 | 603 |
Renal Volume, cm3 | 0.77 0.12 to 1.42 | 0.76 0.42 to 1.10 | 0.58 0.21 to 0.94 | 2.05 0.76 to 3.35 | -0.004 -0.007 to -0.002 | 1.06 0.98 to 1.14 | 0.05 -0.02 to 0.11 | -0.005 -0.02 to 0.01 | 0.08 -0.26 to 0.43 | 0.10 -0.18 to 0.37 |
Maternal/pregnancy - n | 369 | 350 | 413 | 413 | 413 | 404 | 207 | 380 | 586 | 586 |
Renal Volume, cm3 | 0.59 -0.10 to 1.27 | 0.70 0.34 to 1.06 | 0.66 0.29 to 1.05 | 2.37 1.02 to 3.72 | -0.005 -0.008 to -0.002 | 1.06 0.98 to 1.14 | 0.04 -0.02 to 0.11 | -0.005 -0.02 to 0.01 | 0.02 -0.33 to 0.38 | 0.07 -0.21 to 0.36 |
Fully adjusted - n | 355 | 338 | 386 | 386 | 386 | 362 | 182 | 339 | 553 | 553 |
Renal Volume, cm3 | 0.80 0.06 to 1.53 | 0.64 0.25 to 1.02 | 0.79 0.38 to 1.20 | 2.84 1.40 to 4.28 | -0.006 -0.009 to -0.003 | 1.14 1.04 to 1.24 | 0.08 0.01 to 0.15 | 0.002 -0.01 to 0.01 | 0.13 -0.51 to 0.24 | 0.03 -0.27 to 0.34 |