Association between anemia and serum Klotho in middle-aged and older adults

BMC Nephrology

Table 2 Relationship between anemia and S-Klotho (pg/mL) in 3 models, weighted

Exposure	Model 1		Model 2		Model 3
	OR (95% CI)	P-value	OR (95% CI)	P-value	OR (95% CI)	P-value
S-Klotho categories quartiles (IQR)
Quartile 1 (496.7, 613.9)	1.47 (1.18, 1.83)	0.001	1.57 (1.26, 1.96)	<0.001	1.54 (1.21, 1.95)	0.002
Quartile 2 (690.9, 763.4)	1.22 (1.00, 1.49)	0.060	1.27 (1.03, 1.56)	0.032	1.30 (1.02, 1.64)	0.042
Quartile 3 (840.8, 935.5)	0.98 (0.79, 1.22)	0.887	1.02 (0.82, 1.27)	0.881	1.03 (0.81, 1.31)	0.834
Quartile 4 (1060.8, 1330.9)	Reference		Reference		Reference
S-Klotho is divided into quartiles (IQR):
Quartile 1(496.7, 613.9);Quartile 2(690.9, 763.4);Quartile 3(840.8, 935.5);Quartile 4(1060.8, 1330.9).

Model 1: Modified for age, gender, and race.
Model 2: Modified for age, gender, race, marital status(having a partner, others), poverty-to-income ratio (<1.3, 1.3-2.9, \(>=\)3.0), education level (< high school, high school, > high school), alcohol intake (no, yes), smoke (never, former, now), moderate-vigorous physical activity, body mass index (<25.0, 25.0-29.9, \(\ge\)30.0), and high waist circumference.
Model 3: Modified for age, gender, race, marital status (having a partner, others), poverty-to-income ratio (<1.3, 1.3-2.9, \(>=\)3.0), education level (< high school, high school, > high school), alcohol intake (no, yes), smoke (never, former, now), moderate-vigorous physical activity, body mass index (<25.0, 25.0-29.9,\(\ge\)30.0), high waist circumference, phosphorus, calcium, serum iron, albumin, uric acid, urinary albumin/creatinine ratio, estimated glomerular filtration rate, serum 25-hydroxyvitamin D, DFE deficiency, Vitamin B12 deficiency, Iron intake deficiency, angina, heart attack, coronary heart disease, congestive heart failure, stroke, hypertension, hyperlipidemia, diabetes, chronic kidney diseases, cancer, and rheumatoid arthritis.
Abbreviations: OR odd ratio, CI confidence interval

ISSN: 1471-2369