Table 3 RAASi discontinuation, down-titration and up-titration, by potassium category
| Â | Monthly probability of RAASi max discontinuation (%) | Monthly probability of RAASi max down-titration (%) | Monthly probability of RAASi sub-max discontinuation (%) | Source | |||
|---|---|---|---|---|---|---|---|
SoC | Patiromer | SoC | Patiromer | SoC | Patiromer | ||
Month 2–3 | 34.438% (6.589%) | 3.336% (2.421%) | 35.549% (6.589%) | 0.000% (0.000%) | 34.438% (6.589%) | 3.336% (2.421%) | OPAL-HK [43] |
Subsequent months | |||||||
 K +  ≤ 5 | 2.600% (0.009%) | 0.181% | 1.800% (0.026%) | 1.800% | 2.600% (0.009%) | 0.181% | Linde et al. (2019) [23] |
 K +  > 5 to ≤ 5.5 | 3.029% (0.102%) | 0.211% | 2.617% (0.102%) | 2.617% | 3.029% (0.102%) | 0.211% | |
 K +  > 5.5 to ≤ 6 | 4.547% (0.230%) | 0.319% | 5.306% (0.230%) | 5.306% | 4.547% (0.230%) | 0.319% | |
 K +  > 6 | 10.000% (0.663%) | 0.721% | 8.900% (0.638%) | 8.900% | 10.000% (0.663%) | 0.721% | |