Table 2 Pathological features of the seven late-onset OMN cases
Case No. | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 |
|---|---|---|---|---|---|---|---|
Immunoflorescence | IgM+ | IgM+ | C3+ | IgM+, C3++ | C3+ | C3+ | IgM+, C3++ |
Area of cortex (mm2) | 9.13 | 13.52 | 14.89 | 31.19 | 16.78 | 10.78 | 15.11 |
Total number of glomeruli | 7 | 8 | 21 | 17 | 15 | 9 | 15 |
Segmental sclerosis | 1 (perihilar) | 0 | 1 (perihilar) | 1 | 2 (perihilar) | 3 | 1 (perihilar) |
Ischemic sclerosis | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Density of glomeruli (/mm2) | 0.77 | 0.59 | 1.41 | 0.55 | 0.89 | 0.83 | 0.99 |
Mean glomerular diameter (µm) | 216.87 | 211.88 | 224.64 | 217.30 | 260.66 | 232.77 | 244.01 |
*Hypertrophic glomeruli (%) | 40.0% | 66.7% | 60.0% | 60.0% | 90.9% | 50.0% | 66.7% |
Mean short diameter of PT (µm) | 74.55 | 86.89 | 77.69 | 100.53 | 81.27 | 109.08 | 77.11 |
*Dilated PT (%) | 60.0% | 80.6% | 63.6% | 89.4% | 74.3% | 94.2% | 69.2% |
Height of overlying epithelial cells of PT (µm) | 11.82 | 12.27 | 11.94 | 15.41 | 15.93 | 12.78 | 16.16 |
Thickness of GBM (nm) | 475.82 | 355.15 | 351.26 | 377.07 | 389.31 | NA | 411.59 |
Corrected FPW (nm) | 657.84 | 558.89 | 639.21 | 556.39 | 634.24 | NA | 757.54 |