Skip to main content

Table 5 The univariate and multivariate Cox regression analysis for predictors of poor renal outcome in patients with impaired renal function receiving renal biopsy or not

From: Effects of receiving renal biopsy on the prognosis of chronic kidney disease patients with impaired renal function

Characteristics

Univariate analysis

 

Multivariate analysis

 

HR

95% CI

P

 

HR

95% CI

P

Renal biopsy group

Age

1.019

0.980–1.059

0.350

    

Gender (Male)

0.333

0.117–0.948

0.039

    

Hypertension

0.589

0.166–2.095

0.414

    

Diabetes mellitus

18.986

3.676–98.059

< 0.001

 

18.741

3.627–96.830

< 0.001

GC/HCQ/ISD

0.767

0.334–1.764

0.533

    

Haemoglobin

0.990

0.960–1.022

0.533

    

Serum albumin

0.819

0.615–1.091

0.172

    

Hematuria

1.348

0.298–6.095

0.698

    

24 h UPE

1.088

0.991–1.195

0.076

    

eGFR in baseline (mL/min/1.73m2)

0.979

0.947–1.102

0.219

    

Non-Renal biopsy group

Age

0.988

0.965–1.012

0.323

    

Gender (Male)

1.086

0.594–1.984

0.789

    

Hypertension

3.089

1.379–6.916

0.006

    

Diabetes mellitus

4.464

2.433–8.190

< 0.001

    

Haemoglobin

0.983

0.967-1.000

0.046

    

ACEI/ARB

0.788

0.378–1.644

0.525

    

Serum albumin

0.976

0.879–1.085

0.656

    

Hematuria

3.847

1.588–9.320

0.003

    

24 h UPE

1.848

1.261–2.708

0.002

 

1.719

1.025–2.883

0.040

eGFR* in baseline mm2)

0.971

0.951–0.991

0.005

    
  1. HR, hazard ratio; 95% CI, 95% confidence interval; GC, glucocorticoid; HCQ, hydroxychloroquine; ISD, immunosuppressive drugs; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; UPE, urine protein excretion; eGFR estimated glomerular fraction rate.
  2. * The estimated glomerular filtration rate as calculated by the Modification of Diet in Renal Disease equation.