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Table 5 Relationship between ALB and chronic kidney disease progression in different models with the competing risk of mortality

From: The level of serum albumin is associated with renal prognosis and renal function decline in patients with chronic kidney disease

Exposure

Crude model (SHR,95%CI, P )

Model I (SHR,95%CI, P )

Model II (SHR,95%CI, P )

ALB

0.34 (0.29, 0.41)

 < 0.001

0.44 (0.36, 0.54)

 < 0.001

0.60 (0.45, 0.81)

 < 0.001

ALB Quartile

 Q1

Ref

Ref

Ref

 Q2

0.34 (0.25, 0.48)

 < 0.001

0.44 (0.31, 0.62)

 < 0.001

0.69 (0.47, 1.01)

0.06

 Q3

0.19 (0.13, 0.29)

 < 0.001

0.27 (0.18, 0.41)

 < 0.001

0.45 (0.29, 0.70)

 < 0.001

 Q4

0.10 (0.06, 0.15)

 < 0.001

0.15 (0.09, 0.25)

 < 0.001

0.42(0.25, 0.72)

 < 0.05

P for trend

 < 0.001

 < 0.001

 < 0.001

  1. Crude model: we did not adjust other covariants
  2. Model I: we adjust age, BMI, gender, hypertension, SBP, history of CVD, diabetes, and etiology of CKD
  3. Model II: we adjust age, BMI, gender, SBP, diabetes, hypertension, etiology of CKD, use of calcium channel blocker, UPCR, history of CVD, eGFR, urinary occult blood, Hb, use of RAAS inhibitor, use of diuretics
  4. CI Confidence, Ref Reference, SHR Subdistribution hazard ratios