Diagnostic value of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for detection of renal failure in hypertensives: a case–control study in a regional hospital in Ghana

Table 2 Diagnostic performances of NGAL in the assessment of renal impairment using MDRD, CKD-EPI creatinine and Cockroft-Gault eGFR equations

Variables	Sensitivity (95%CI)	Specificity (95%CI)	PPV	NPV	TP	TN	FP	FN	Youden Index	Associated Criterion
		Based on MDRD Equation
NGAL	0.91(0.72–0.98)	0.68(0.59–0.76)	0.36	0.97	21	80	37	2	0.60	109.4
		Based on CKD-EPI Equation
NGAL	1.00(0.80–1.00)	0.72(0.63–0.79)	0.36	1.00	19	87	34	0	0.72	120.2
		Based on Cockroft-Gault Equation
NGAL	0.83(0.65–0.93)	0.72(0.63–0.79)	0.43	0.94	24	80	31	5	0.55	118.6

PPV positive predictive value, NPV negative predictive value, TP True Positive, TN True Negative, FP False Positive, FN-False Negative

ISSN: 1471-2369