Fig. 2
From: A potential link between fibroblast growth factor-23 and the progression of AKI to CKD
Renal fibrosis occurred in IRI mice with increased FGF-23 levels. (a) Representative photomicrographs of haematoxylin and eosin (H&E)- and Masson’s trichrome-stained kidney sections of sham and IRI mice. (b) Representative photomicrographs of immunochemical staining of kidney sections from sham and IRI mice. (c) Representative gross appearance of kidneys in the indicated groups. (d) Average concentrations of serum FGF-23 in sham and IRI mice (mean ± SD; n = 6 mice per group; *P < 0.05). (e) Renal expression of COL1A1 and COL4A1 in sham and IRI mice was assayed by Q-PCR (mean ± SD; n = 6 mice per group; *P < 0.05; **P < 0.01)