Fig. 4
From: A potential link between fibroblast growth factor-23 and the progression of AKI to CKD
PD173074 reduced renal fibrosis in AKI-CKD mice. (a) Representative photomicrographs of Masson’s trichrome-stained kidney sections from control, IRI-treated and IRI/PD173074-treated mice. (b) Kidney expression of E-cadherin (E-cad), -smooth muscle actin (α-SMA), β-catenin, phosphorylated Smad3, and NGAL in control, IRI-treated and IRI/PD173074-treated mice. (c) Quantification of the data in (b). (*P < 0.05; **P < 0.01). (d) Average concentrations of serum FGF-23 in mice (mean ± SD; n = 6 mice per group; **P < 0.01)