Table 2 Comparison of the initial manifestations of classical patients with Fabry disease at different sexes and ages [N = 219, n/N (%)]
|  | Males(n = 161) | Females(n = 58) | ||||||
|---|---|---|---|---|---|---|---|---|
Preschool group (n = 43) | Juvenile group (n = 100) | Young group (n = 18) | Middle-aged / elderly group (n = 0) | Preschool group (n = 8) | Juvenile group (n = 32) | Young group (n = 14) | Middle-aged / elderly group (n = 4) | |
Acroparesthesia (limb pain) | 36/43 (83.72) | 92/100 (92.00) | 3/18 (16.67) a, b | / | 5/8 (62.50) | 29/32 (90.63) | 7/14 (50.00) b | 1/4(25.00) b |
Anhidrosis/ hypohidrosis | 12/43 (27.91) | 13/100 (13.00) | 0/18 a | / | 2/8 (25.00) | 2/32 (6.25) | 3/14 (21.43) b | 0/4 |
Renal invo | 1/43 (2.33) | 3/100 (3.00) | 12/18 (66.67) a, b | / | 0/8 | 0/132 | 1/14 (7.14) | 0/4 |
Cardiovascular invo | 0/43 | 0/100 | 4/18 (22.22) a, b | / | 0/8 | 0/32 | 2/14 (14.29) b | 1/4(25.00) b |
Angiokeratomas | 2/43 (4.65) | 6/100 (6.00) | 1/18 (5.56) | / | 0/8 | 1/32 (6.45) | 3/14 (21.43) b | 0/4 |
Neuropsychiatric invo | 0/43 | 1/100 (1.00) | 0/18 | / | 0/8 | 0/32 | 0/14 | 1/4(25.00) b |
Digestive system invo | 0/43 | 0/100 | 0/18 | / | 1/8 (12.50) | 3/32 (9.38) | 0/14 | 0/4 |
Others manifestations | 0/43 | 0/100 | 0/18 | / | 0/8 | 1/32 (6.45) | 0/14 | 1/4(25.00) |