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Fig. 2 | BMC Nephrology

Fig. 2

From: Alport syndrome misdiagnosed with IgA nephropathy from familial history: a case report and brief review

Fig. 2

A Immunofluorescence study for IgG, IgA, IgM, C3c, C4c, C1q, Kappa and Lambda shows negative reaction in glomeruli and tubulointerstitium (100X). B Immunofluorescence study for α2 chain of collagen type IV (red fluorochrome) shows normal staining pattern (arrow). α5 chain of collagen type IV (green fluorochrome) shows weak staining in GBM and distal tubule basement membrane (arrow head) (100X). C Ultrastructural evaluation by TEM study shows irregular GBM with alternating foci of thinning (arrow) and thickening (arrow head) (8000X)

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