Table 1 Characteristics of included studies
Study | Year | Author's country | Sample Size, N | Male, N(%) | Age, Years, Mean ± SD or Median(IQR) | Baseline eGFR, mL/min/1.73 m2, Mean ± SD or Median(IQR) | ICIs-related AKI, N (%) | Cases underwent renal biopsy, N (%) |
|---|---|---|---|---|---|---|---|---|
Meraz-Muñoz [10] | 2020 | Canada | 309 | 186(60.2) | 61(51–69) | 88(75–99) | 51(16.5) | 6(11.8) |
Abdelrahim [3] | 2021 | USA | 1664 | 1098(66.0) | NA | NA | 72(4.3) | 25(34.7) |
Seethapathy [5] | 2019 | USA | 1016 | 616(60.6) | 63 ± 13 | 82 ± 22 | 169(16.6) | 1(0.6) |
Cortazar [9] | 2020 | USA | 414 | 254(61.4) | NA | NA | 138(33.3) | 60(43.5) |
Koks [4] | 2021 | Netherlands | 676 | 420(62.1) | 64(53–71) | 90(75–101) | 96(14.2) | 1 (1.0) |
Shimamura [13] | 2021 | Japan | 152 | 114(75.0) | 67 ± 10 | 72(55–87) | 27(17.8) | 1 (3.7) |
Stein [11] | 2020 | France | 239 | 132(55.2) | 68(58.5–77) | 84(70–94) | 41(17.1) | 3(7.3) |
Seethapathy [12] | 2020 | USA | 599 | 298(49.7) | 65 ± 13 | 88 ± 26 | 36(6.0) | 1(2.8) |
Gupta [14] | 2021 | USA | 858 | 517(60.3) | NA | NA | 429(50.0) | 151(35.2) |