Table 4 Comparison of clinical and biochemical parameters at baseline and the end of the study

Dry weight, kg

59.9 ± 1.55

60.4 ± 1.49

0.022

58.5 ± 1.55

58.8 ± 1.49

0.211

0.444

BMI, kg/m²

21.1 ± 0.50

21.3 ± 0.47

0.019

20.6 ± 0.50

20.7 ± 0.47

0.210

0.337

Albumin, g/dl

3.0 ± 0.05

3.5 ± 0.06

< 0.001

3.0 ± 0.05

3.1 ± 0.06

0.134

< 0.001

Prealbumin, mg/dl

10.9 ± 0.66

14.7 ± 0.61

< 0.001

12.6 ± 0.66

12.5 ± 0.61

0.612

0.012

TIBC, ug/dl

185 ± 3.64

211 ± 4.01

< 0.001

186 ± 3.64

198 ± 4.01

0.001

0.031

Hs-CRP, mg/l

6.5 ± 0.45

4.9 ± 0.34

0.001

6.4 ± 0.45

6.19 ± 0.34

0.652

0.014

Cholesterol, mg/dl

106 ± 4.22

120 ± 4.41

0.016

99.6 ± 4.22

108 ± 4.41

0.106

0.064

Ferritin, ug/l

544 ± 86.1

482 ± 78.3

< 0.001

578 ± 86.1

554 ± 78.3

0.064

0.521

Hemoglobin, g/dl

9.3 ± 0.28

9.8 ± 0.16

0.048

9.1 ± 0.29

9.7 ± 0.16

0.025

0.714

Sodium, mEq/l

140 ± 0.46

141 ± 0.46

0.265

141 ± 0.46

140 ± 0.46

0.265

0.514

Potassium, mEq/l

4.3 ± 0.11

4.4 ± 0.11

0.765

4.5 ± 0.11

4.6 ± 0.11

0.647

0.238

Phosphorus, mg/dl

6.05 ± 0.26

6.09 ± 0.25

0.895

6.06 ± 0.26

6.08 ± 0.25

0.947

0.978

Calcium, mg/dl

7.7 ± 0.16

7.8 ± 0.15

0.792

7.7 ± 0.16

7.7 ± 0.15

0.914

0.755

iPTH, pg/ml

482 ± 44.5

514 ± 34.7

0.114

446 ± 44.5

458 ± 34.7

0.554

0.259

Creatinine, mg/dl

6.30 ± 0.23

6.65 ± 0.18

0.009

6.13 ± 0.23

6.15 ± 0.18

0.887

0.063

Creatinine/Body surface area, mg/dl/m²

3.7 ± 0.14

3.9 ± 0.12

0.016

3.72 ± 0.14

3.73 ± 0.12

0.965

0.166

nPNA, g/kg/day

0.77 ± 0.02

0.90 ± 0.02

< 0.001

0.72 ± 0.02

0.78 ± 0.02

< 0.001

0.092

Lean body mass, kg

48.5 ± 1.05

48.7 ± 1.04

0.054

47.6 ± 1.05

47.7 ± 1.04

0.227

0.536

French PEW score, n (%)

0–1

24(80)

13(43.3)

24(80)

24(80)

2

5(16.7)

14(46.7)

6(20)

6(20)

3

1(3.3)

2(6.7)

0(0)

0(0)

4

0(0)

1(3.3)

0(0)

0(0)

French PEW score, median (minimum-maximum)

1(0–3)

2(0–4)

0.002

1(0–2)

1(0–2)

0.564

0.001