Table 1 Baseline characteristics of the study patients according to serum β2M levels
Characteristic | Study population (n = 521) | β2M range (mg/L) | |||
|---|---|---|---|---|---|
T1 (< 34.9) (n = 173) | T2 (34.9–45.4) (n = 172) | T3 (> 45.4) (n = 176) | P | ||
Age, years | 60 (19) | 57 (20) | 60 (19) | 62 (17) | 0.02 |
Male, n (%) | 303 (58.1) | 106 (61.3) | 97 (56.4) | 100 (56.8) | 0.60 |
BMI, Kg/m2 | 23.4 (5.2) | 24.3 (4.9) | 23.6 (5.7) | 22.5 (5.2) | < 0.01 |
Dialysis duration, months | 54 (67) | 46 (66) | 53 (75) | 62 (60) | < 0.01 |
Primary disease, n (%) | 0.28 | ||||
Diabetic nephropathy | 167 (32.1) | 57 (33.0) | 54 (31.4) | 56 (31.8) | |
Glomerulonephritis | 214 (41.1) | 77 (44.5) | 69 (40.1) | 68 (38.6) | |
Hypertensive benign renal arteriosclerosis | 78 (15.0) | 23 (13.3) | 32 (18.6) | 23 (13.1) | |
Others | 62 (11.7) | 16 (9.2) | 17 (9.9) | 29 (16.5) | |
hypertension status, n (%) | 376 (72.2) | 121 (69.4) | 129 (75.0) | 126 (71.6) | 0.49 |
diabetes mellitus status, n (%) | 178 (34.1) | 64 (37.0) | 62 (36.1) | 52 (29.6) | 0.56 |
dialyzer mode, n (%) | < 0.01 | ||||
high-flux dialyzers | 190 (36.5) | 110 (63.6) | 62 (36.1) | 18 (10.2) | |
low-flux dialyzers | 331 (62.3) | 63 (36.4) | 110 (64.0) | 158 (89.8) | |
Hemoglobin, g/L | 112 (19) | 114 (15) | 110 (20) | 112 (22) | 0.01 |
Albumin, g/L | 41.8 (4.3) | 42 (3.7) | 41.7 (4.6) | 41.9 (4.1) | 0.66 |
Urea nitrogen, mmol/L | 26.1 (7.6) | 25.4 (6.6) | 26.3 (7.5) | 26.7 (9.1) | 0.06 |
Creatinine, umol/L | 932.3 ± 244.3 | 939.4 ± 262.8 | 927.8 ± 243.4 | 930.1 ± 227.0 | < 0.01 |
CRP, ug/L | 3.1 (5.2) | 3.1 (2.1) | 3.1 (6.8) | 4.0 (6.6) | < 0.01 |
Kt/v | 1.3 (0.3) | 1.3 (0.3) | 1.3 (0.3) | 1.3 (0.4) | 0.79 |
β2M, mg/L | 40.1 (17.1) | 29.7 (5.3) | 40.1 (5.9) | 53.1 (9.4) | < 0.01 |