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Table 3 Stratified analysis of patient background and various interventions (population with renal function displacement)

From: Long-term effects of contrast media exposure on renal failure progression: a retrospective cohort study

 

Parameter

CAT group

Non-CAT group

P-value

Case

       
 

Sample (n)

63

  

63

   
 

Age (years)

54.4

±

9.0

54.5

±

7.9

0.93

 

Sex: male (%)

71.4

  

77.8

  

0.41

 

Observation period (years)

5.1

±

2.0

4.6

±

1.8

0.16

 

Baseline estimated GFR (mL/min/1.73 m2)

42.1

±

46.6

31.5

±

41.4

0.22

Disease

       
 

Diabetic nephropathy (%)

27.0

  

20.6

  

0.40

 

Glomerular nephritis (%)

22.2

  

12.7

  

0.16

 

Nephrosclerosis (%)

1.6

  

6.3

  

0.37

 

Hypertension (%)

98.4

  

100.0

  

1.00

 

Diabetes (%)

60.3

  

61.9

  

0.86

Contrast agent

       
 

Number of contrast agent exposures (time/year)

1.9

±

1.7

   

―

 

Amount of contrast agent (mL/year)

40.1

±

54.2

   

―

 

Amount of rehydration (mL/year)

3983.4

±

5635.8

969.1

±

1264.9

< 0.01

Main medicine

       
 

Hyperkalaemia drug (%)

42.9

  

49.2

  

0.48

 

Phosphate binder (%)

30.2

  

39.7

  

0.26

 

Erythropoiesis-stimulating agent (%)

63.5

  

69.8

  

0.45

 

Spherical carbon adsorbent (AST-120) (%)

27.0

  

36.5

  

0.25

 

Antihypertensive (%)

88.9

  

95.2

  

0.19

 

Diuretic (%)

69.8

  

58.7

  

0.19

 

Diabetes drug (%)

58.7

  

55.6

  

0.72

 

Non-steroidal anti-inflammatory drug (%)

57.1

  

58.7

  

0.86

 

Antibacterial drug (%): Aminoglycosides, Glycopeptides, Others

15.9

  

11.1

  

0.43

 

Anticancer drug (%)

1.6

  

1.6

  

1.00

Main surgery

       
 

Revascularisation (%)

12.1

  

0.0

  

< 0.01

 

Cardiovascular implantable electronic device, others (%)

6.9

  

0.9

  

< 0.01

 

Heart valve replacement, valvuloplasty (%)

2.2

  

0.0

  

0.06

Main prevention

       
 

Lifestyle disease prevention (education, guidance) (%)

6.3

  

3.2

  

0.68

  1. Note: Most CATs in this study were imaging tests. Therefore, descriptions in this table focused on therapeutic interventions