Fig. 1

Histological images from the renal biopsy. (A) Staining of HE, Masson, PAS, and PASM. Light microscopy shows the glomerulus with thickening of basement membranes and spikes. (B) Staining of copper. No obvious copper deposition was found in renal tubular epithelial cells and glomerular sacs (C) Immunofluorescence micrographs. immunofluorescence microscopy shows C1q(++), C3(++), IgM(+), and IgG(++) deposited along the glomerular capillary. (D) Electron micrographs. Electron microscopy shows glomerular basement membrane irregularly thickened and podocyte foot process effacement. Electron-dense deposits were noted in the subepithelial, basement membrane, subendothelial and mesangial regions