| Journal | N for donor | N for control | Follow up for donor | Follow up for control | Definition of CKD or ESRD | ESRD (or CKD) among donor | ESRD (or CKD) among control | Covariates for HR | Unadjusted HR | Adjusted HR | Cause of ESRD (or CKD) for donor | Cause of ESRD (or CKD) for control |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lam et al. 2012 [15] | Nephrol Dial Transplant | 2027 | 20,270 | 6.9 (median) | 6.5 (median) | ESRD: Acute dialysis in follow-up up period (continuous veno-venous or intermittent) | 1 | 14 |  |  | 0.58 (95%CI, 0.08–4.47) |  |  |
Muzaale et al. 2014 [13] | JAMA | 96,217 | 96,217 | 7.6 [3.9–11.5] | 15.0 [13.7–15.0] | ESRD: Earliest of initiation of maintenance dialysis, placement on the waiting list, receipt of a living or deceased donor kidney transplant | 99 | 36 |  | 2.75 (95% CI, 1.96–3.85) |  |  |  |
Kim et al. 2019 [16] | Renal Epidemiology | 1901 | 32,621 | 15.1 [1.5–43.9] | 24.9 [0.1–26.0] | CKD: estimated glomerular filtration rate of < 60 ml/min/1.73m2 and/or the presence of proteinuria in two or more consecutive visits | 3 | 2969 | Model I |  | 13.63 (95%CI, 4.39–42.26) |  |  |
Age, Sex, Center, Year of screening exam | |||||||||||||
Model II | 8.63 (95%CI, 2.78–26.84) | ||||||||||||
 + Baseline eGFR, Smoking status, Alcohol intake, Regular exercise, Education level, Hx of DM, HTN, Medication use of DM,HTN, Dyslipidemia | |||||||||||||
Model III | 8.72 (95%CI, 2.80–27.12) | ||||||||||||
 +  Renal compensation hypertrophy | |||||||||||||
Mjoen et al. 2013 [14] | Kidney International | 1901 | 32,621 | 15.1 [1.5–43.9] | 24.9 [0.1–26.0] | ESRD: initiation of renal replacement therapy (dialysis, transplantation) | 9 | 22 | Inclusion year, Age, Sex, sBP, BMI, Smoking | 18.99 (95%CI, 8.63–41.76) | 11.38 (95%CI, 4.37–29.63) | Glomerulonephritis (3) Systemic lupus erythematosus (1) Wegner's granulomatosis (1) ANCA-positive vasculitis (1) Sarcoidosis(1) DM/Nephrosclerosis (2) | Glomerulonephritis (5) Pyelonephritis (4) PCKD (4) HTN (3) DM (1) Amyloidosis (1) Systemic lupus erythematosus (1) Drug induced nephropathy (1) Medullary cystic disease (1) |
Haugen et al. 2020 [17] | Transplantation International | 1029 | 16,084 | 11.3 (mean) | 16.4 (mean) | CKD: eGFR < 60 ml/min | 216 | 236 |  | 14.31 (95% CI, 9.71–21.08) |  |  |  |