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Table 2 Pruritus assessment using VAS and 5-D scores at baseline and study end in both groups

From: The effectiveness of sertraline in alleviating uremic pruritus in hemodialysis patients: a randomized clinical trial

 

Sertraline group (n = 30)

Placebo group (n = 30)

Comparison between groups

 

Baseline

Week 8

p0

Change (Δ)

Baseline

Week 8

p0

Change (Δ)

p1

p2

p3

VAS score (cm)

5.27 ± 2.75

3.45 ± 2.03

 < 0.001

↓1.82

4.57 ± 1.94

4.36 ± 2.34

0.469

↓0.21

0.435

0.175

0.002

5D itch scale (point)

17.13 ± 6.99

12.45 ± 3.78

 < 0.001

↓4.68

14.93 ± 4.31

15.50 ± 4.81

0.584

↑0.57

0.410

0.009

 < 0.001

  1. Data were expressed in Mean ± SD
  2. p0: p value for comparing between Baseline and Week 8 in each group
  3. p1: p value for comparing between sertraline group and Placebo group at Baseline
  4. p2: p value for comparing between sertraline group and Placebo group at Week 8
  5. p3: p value for comparing the change (Δ) between sertraline group and Placebo group
  6. VAS: visual analogue scale
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BMC Nephrology

ISSN: 1471-2369

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