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Table 4 Bivariate logistic regression of characteristics associated with reduced eGFR, reduced eGFRDEGREE, and reduced eGFRKenya

From: Prevalence and predictors of chronic kidney disease of undetermined causes (CKDu) in Western Kenya’s “sugar belt”: a cross-sectional study

Variable

Reduced eGFR

Reduced eGFRDEGREE

Reduced eGFRKenya

n

OR (95%CI)

p -value

n

OR (95%CI)

p -value

n

OR (95%CI)

p -value

Sex

 Female

392

1.64 (1.01, 2.65)

0.04

312

1.77 (1.00, 3.14)

0.05

244

2.12 (0.93, 4.85)

0.07

 Male

390

Ref

 

300

Ref

 

264

Ref

 

Sublocation

 Muhoroni East and Owaga

549

2.23 (1.21, 4.14)

0.01

414

2.02 (1.02, 4.01)

0.04

341

2.12 (0.78, 5.74)

0.13

 Tonde

233

Ref

 

198

Ref

 

167

Ref

 

Age

 Per 1-year increase

782

1.11 (1.08, 1.14)

 < .0001

612

1.12 (1.09, 1.16)

 < .0001

508

1.14 (1.09, 1.19)

 < .0001

Body Mass Index (BMI) (kg/m2)

 Underweight (≤ 18.5), overweight (> 25 to ≤ 30), or obese (> 30)

307

2.11 (1.31, 3.40)

0.002

222

2.48 (1.41, 4.34)

0.0015

187

5.07 (2.09, 12.31)

0.0003

 Normal (> 18.5 to ≤ 25)

475

Ref

 

390

Ref

 

321

Ref

 

Blood pressure

  ≥ 140 or ≥ 90 or on hypertensive medication

111

1.54 (0.84, 2.81)

0.16

-

-

-

-

-

-

  < 140 and < 90 and not on hypertensive medication

671

Ref

 

-

Ref

-

-

Ref

-

Previous diabetes diagnosis by a physician

 Yes

8

5.68 (1.33, 24.23)

0.01

-

-

-

-

-

-

 No

774

Ref

 

-

Ref

-

-

Ref

-

Self-reported HIV

 Yes

125

4.68 (2.83, 7.74)

 < .0001

104

7.17 (4.00, 12.84)

 < .0001

-

-

-

 No

657

Ref

 

508

Ref

 

-

Ref

-

Medication against HIV

 Yes

122

4.25 (2.56, 7.06)

 < .0001

102

6.18 (3.46, 11.07)

 < .0001

-

-

-

 No

659

Ref

 

509

Ref

 

-

Ref

-

 Missing

1

  

1

  

-

-

-

Tuberculosis

 Yes

30

1.89 (0.70, 5.09)

0.20

25

2.69 (0.97, 7.46)

0.05

11

a

 

 No

752

Ref

 

587

Ref

 

497

Ref

 

Prescribed medications

 Yes

248

3.48 (2.15, 5.63)

 < .0001

189

3.86 (2.18, 6.82)

 < .0001

89

0.84 (0.28, 2.52)

0.76

 No

534

Ref

 

423

Ref

 

419

Ref

 

Antibiotic medication for infection

 Yes

466

1.46 (0.89, 2.41)

0.13

364

1.58 (0.87, 2.88)

0.13

287

1.78 (0.76, 4.17)

0.18

 No

316

Ref

 

248

Ref

 

221

Ref

 

Painkillers most days

 

 Yes

347

1.24 (0.78, 2.00)

0.35

271

1.45 (0.83, 2.53)

0.18

221

2.16 (0.96, 4.86)

0.06

 No

435

Ref

 

341

Ref

 

287

Ref

 

Herbal or traditional remedies

 Yes

269

0.85 (0.51, 1.41)

0.53

212

0.62 (0.33, 1.16)

0.13

191

0.72 (0.31, 1.70)

0.46

 No

513

Ref

 

400

Ref

 

317

Ref

 

Consumption of sugary drinks in past 7 days

 5 or more drinks

57

2.09 (1.01, 4.33)

0.04

44

2.05 (0.87, 4.85)

0.10

32

1.25 (0.28, 5.56)

0.76

 None to 4 drinks

725

Ref

 

568

Ref

 

476

Ref

 

Currently smoke tobacco

 Yes

39

0.23 (0.03, 1.70)

0.15

33

0.30 (0.04, 2.26)

0.24

28

a

 

 No

743

Ref

 

579

Ref

 

480

Ref

 

Occupational physical intensity group

 High-intensity

390

1.29 (0.75, 2.22)

0.36

298

1.73 (0.87, 3.41)

0.12

231

1.39 (0.55, 3.47)

0.48

 Low- and moderate-intensity

214

Ref

 

158

Ref

 

138

Ref

 

 Missing/Unclassifiable

178

  

156

  

139

  
  1. aQuasi-complete separation of data points detected. The odds ratio (OR) could not be calculated
  2. Reduced kidney function was defined as eGFR < 90 mL/min/1.73m2
  3. Ref reference category for odds ratio (OR) calculation