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Table 3 Multivariable logistic regression analysis showing the association of serum TSP-2 level with DN (n = 494)

From: Extracellular status of thrombospondin-2 in type 2 diabetes mellitus and utility as a biomarker in the determination of early diabetic kidney disease

Variables

OR (95%CI)

p value

Model 1

 Age

1.06 (1.03–1.09)

 < 0.001

 T2DM duration

1.00 (1.00–1.01)

0.008

 BMI, kg/m2

1.09 (1.02–1.17)

0.015

 TSP-2a, ng/mL

2.26 (1.63–3.14)

 < 0.001

Model 2

 Plateletsa, 109/L

1.66 (1.06–2.60)

0.026

 UACRa, mg/g

2.52 (1.82–3.49)

 < 0.001

 TSP-2a, ng/mL

1.94 (1.24–3.04)

0.004

  1. aLog transformed. Model 1, variables included in the analysis were basic factors including age, sex, T2DM duration, and BMI, and drug use of statin, ACEIs/ARBs, and TSP-2 levels. Model 2, variables included in the analysis were those in model 1 plus TG, SUA, SCR, eGFR, Platelets, and UACR levels
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BMC Nephrology

ISSN: 1471-2369

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