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Table 3 Univariate logistic regression analysis of clinical and laboratory features against mortality

From: Clinical features of COVID-19 among patients with end-stage renal disease on hemodialysis in the context of high vaccination coverage during the omicron surge period: a retrospective cohort study

Variables

Alive

N = 101

Died

N = 5

p

OR (95% CI)a

Clinical features

 Age (years, mean ± SD)

65.1 ± 12.0

77.0 ± 4.8

0.034

1.12 (1.02, 1.26)

 Male sex (N, %)

49 (48.5%)

1 (20.0%)

0.200

0.27 (0.013, 1.87)

 Fever at presentation (N, %)

27(26.7%)

3 (60.0%)

0.130

4.11 (0.65, 32.5)

 No. of vaccinations (mean ± SD)

2.5 ± 1.2

0.6 ± 1.2

0.009

0.36 (0.13, 0.71)

 No. of comorbidities (mean ± SD)

1.2 ± 0.8

2.6 ± 0.8

0.004

5.75 (1.97, 24.4)

 Hypertensionc (N, %)

84 (83.2%)

1 (20.0%)

0.009

0.05(0.00, 0.37)

 Diabetes mellitus (N, %)

81 (80.2%)

3 (60.0%)

0.300

0.37 (0.06, 2.95)

 Cardiovascular diseases (N, %)

14 (13.9%)

4 (80.0%)

0.005

24.9 (3.38, 50.6)

 Psychosis (N, %)

6 (5.9%)

1 (20%)

0.200

3.96 (0.187, 32.7)

 Severe obesityb (N, %)

6 (5.9%)

0 (0%)

0.85f

1.34(6.64, 26.9)f

Laboratory features (mean ± SD)

 Calcium (mg/dL)

9.0 ± 1.0

8.1 ± 0.6

0.058

0.41 (0.14, 1.01)

 Albumin (mg/dL)

3.4 ± 0.3

3.0 ± 0.2

0.028

0.07 (0.00, 0.737)

 C-reactive protein (mg/dL)

2.0 ± 1.8

3.5 ± 1.9

0.088

1.42 (0.93, 2.14)

 Presepsin (pg/mL)

2,633 ± 2,211

4,492 ± 3,356

0.110

1.00 (1.00, 1.00)

 Procalcitonin (μg/L)

0.8 ± 1.2

1.3 ± 0.8

0.400

1.25 (0.62, 1.9)

 D dimer (μg/mL)

1.3 ± 2.1

1.9 ± 0.9

0.500

1.09 (0.67, 1.37)

 Aspartate transaminase (μ/L)

19.5 ± 8.3

47.4 ± 29.9

0.005

1.09 (1.04, 1.19)

 Alanine transaminase (μ/L)

18.1 ± 8.3

20.0 ± 7.8

0.600

1.02 (0.91, 1.12)

 Lactatedehydrogenase (μ/L)

346.7 ± 95.4

633.6 ± 278.5

0.006

1.01 (1.00, 1.02)

 Brain natriuretic Peptide (pg/ml)

12,161 ± 11,967

28,706 ± 13,596

0.019

1.00 (1.00, 1.00)

 Hemoglobin (mg/dl)

10.4 ± 1.1

11.1 ± 1.1

0.140

1.83 (0.82, 4.22)

 Red cell distribution width (%)

14.3 ± 1.8

17.7 ± 2.7

0.003

1.99 (1.32, 3.38)

 Total lymphocyte count (/mm3)

1,151.2 ± 523.3

1041.5 ± 327.5

0.700

1.00 (1.00, 1.00)

 Total platelet count (103/mm3)

163.4 ± 54.8

143.2 ± 47.7

0.400

1.00 (097, 1.01)

 Plateletcrit (%)

0.2 ± 0.1

0.1 ± 0.1

0.400

0.00 (0.00,10,200)

 Platelet distribution width (%)

10.7 ± 2.0

11.6 ± 1.1

0.300

1.22 (0.08, 1.77)

 Neutrophil lymphocyte ratio

5.6 ± 3.1

5.1 ± 1.4

0.700

0.91 (0.50, 1.20)

 Leukocyte glucose indexd

931.5 ± 641.2

631.8 ± 272.6

0.300

1.00 (1.00, 1.00)

 CT scoree(mean ± SD)

1.1 ± 2.6

1.6 ± 1.5

0.600

1.07 (0.713, 1.38)

  1. Categorical variables are described as counts (N) and frequencies (%), while numeric variables are described as means ± standard deviation (SD)
  2. aOR: odds ratio
  3. bSevere obesity: body mass index > 30.3 kg/m2
  4. cHypertension: refer to the discussion
  5. dLeukocyte glucose index is defined as the product between blood leukocyte counts and glucose levels divided by 1000
  6. eCT score: lung computed tomography score
  7. The figures in bold represent statistical significance p<0.05
  8. fSource: own calculation