Skip to main content
Fig. 1 | BMC Nephrology

Fig. 1

From: Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease

Fig. 1

Highly variable genes and SCENIC UMAP plots with cell type classifications. A UMAP visualization of cells using the same principal components as input to the clustering analysis; B Dot plot of selected marker genes within each cell type. The size of the dot encodes the percentage of cells within a cell type, while the color encodes the average expression level across all cells within a cell type; C UMAP visualization of cells using the SCENIC regulon activity matrix. PODO, podocytes; MES, mesangial cells; ENDO1, glomerular endothelial cells; ENDO2, endothelia cells type 2; PEC, parietal epithelial cells; IMM, immune cells; PCT1, proximal tubule epithelial cells type 1; PCT2, proximal tubule epithelial cells type 2; TAL, thick ascending limb cells; CNT, connecting tubule cells; DCT, distal convoluted tubule cells; CD-PC, collecting duct principal cells; CD-ICA, collecting duct intercalated cells type A; CD-ICB, collecting duct intercalated cells type B; INT, interstitial cells

Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us