Skip to main content
Fig. 3 | BMC Nephrology

Fig. 3

From: Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease

Fig. 3

A The regulon activity changes in kidney proximal convoluted tubule epithelial cell type 1 in diabetic patients; PCT1, proximal convoluted tubule epithelial cell type 1; B The regulon activities of FXR (NR1H4) across kidney cell types; C The regulon activities of CREB5 across kidney cell types; D mRNA expression of FXR and CREB5 across kidney cell types in diabetic and control conditions; E Gene regulatory network of the TFs FXR (NR1H4) and CREB5 and their target genes. The pink color of a shade indicates that the gene was upregulated in diabetic PCT cells, and the intensity of shade denotes the relative change across genes

Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us