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Fig. 6 | BMC Nephrology

Fig. 6

From: Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease

Fig. 6

Knockdown of CREB5 sensitized HK2 cells to AGE-induced apoptosis. A Immunoblotting showed that siCREB5 significantly reduced CREB5 protein in HK2 cells. B CREB5 knockdown markedly enhanced the AGE-induced activation of caspase-3 and PARP1. All the results represent the data from three independent experiments. *p < 0.05; **p < 0.01; #p < 0.05, statistical significance

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BMC Nephrology

ISSN: 1471-2369

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