Fig. 7

CREB5 and FXR knockdown aggravated AGE-induced EMT in HK2 cells. Immunoblotting of fibronectin, vimentin, E-cadherin in HK2 cells treated with siCREB5 (A) and siFXR (B) for 24 h, followed by treatment with 200 µg/ml AGE for 24 h. The results represent the data from three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001; #p < 0.05; ###p < 0.001. statistically significant