Fig. 3
From: Impact of serum sodium concentrations, and effect modifiers on mortality in the Irish Health System
Adjusted hazard ratios for all-cause and cardiovascular mortality by serum sodium stratified by eGFR category. Solid line (—) denotes Hazard ratio and dash line (-—-) denotes 95% confidence intervals (CIs). Filled circles denote statistical significance (P < 0.05) compared with the reference (blue circle). Estimates are based on unadjusted and adjusted penalised spline models for the association between time dependent serum sodium and all-cause mortality. Hazard ratios were adjusted for age, sex, serum albumin, haemoglobin, serum potassium, serum calcium, white blood cell count, alanine aminotransferase, alkaline phosphatase, and clinical setting at baseline