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Table 1 Clinical characteristics and laboratory data of patients with COVID-19

From: Clinical characteristics and outcomes of COVID-19 patients with varying renal functions statuses during the Omicron pandemic in Shanghai

 

Group A

n = 384

Group B

n = 220

Group C

n = 92

P value

Age (y)

41.21 ± 14.44#

59.30 ± 15.0#

64.57 ± 12.81

0.000

Male (n, %)

219, 57.0%

126, 57.3%

57, 61.9%

> 0.05

Comorbidities

  Hypertension (n,%)

34, 8.9%*

75, 34.1%*

73, 79.4%

0.000

  Diabetes (n,%)

15, 3.9%*

26, 11.8%*

30, 32.6%

0.000

  CVD (n,%)

2, 0.5%*

22, 10%

17, 18.5%

0.000

  Malignancies (n,%)

2, 0.5%*

10, 4.5%

3, 3.2%

0.01

Vaccine of COVID-19

0.000

  0 Shot (n,%)

54, 14.1%*

82, 37.3%*

85, 92.4%

  1 Shot (n,%)

15, 3.9%

9, 4.1%

2, 2.2%

  2 Shots (n,%)

131, 34.1%*

56, 25.5%*

3, 3.2%

  >=3 Shots (n,%)

184, 47.9%*

73, 33.1%*

2, 2.2%

Symptoms

  Fever (n, %)

44, 11.4%

29, 13.1%

11, 11.9%

> 0.05

  Respiratory symptoms (n,%)

148, 38.5%

92, 41.8%

42, 45.6%

> 0.05

Clinical Classification

0.000

  Asymptomatic (n,%)

200, 52.1%*

93, 42.3%*

15, 16.3%

  Mild (n,%)

165, 42.9%

84, 38.2%

32, 34.8%

  Moderate (n,%)

18, 4.7%*

35, 15.9%*

32, 34.8%

  Severe (n,%)

0*

2, 0.9%

3, 3.3%

  Critical (n,%)

1, 0.3%*

6, 2.7%*

10, 10.8%

Treatment

  Antibiotics (n,%)

4, 1.0%*

8, 3.6%*

24, 26.1%

0.000

  Paxlovid (n,%)

24, 6.3%

18, 8.1%

7, 7.6%

> 0.05

Laboratory data

  ALT (iu/L)

21.5(18)#

20(16)#

13(11.2)

0.000

  AST (iu/L)

21(9)#

22(9.7)#

14(8)

0.000

  Albumin (g/L)

41.53 ± 3.02#

39.92 ± 4.22#

36.94 ± 4.35

0.000

  Blood urea nitrogen (mmol/L)

4.40 ± 1.11#

5.63 ± 2.03#

38.81 ± 13.13

0.000

  Creatinine (umol/L)

71.02 ± 12.03#

87.35 ± 15.59#

1253.6 ± 442.7

0.000

  eGFR (ml/min/1.73m2)

106.91 ± 13.01#

76.07 ± 12.50#

3.46 ± 1.83

0.000

  Sodium (mmol/L)

139.74 ± 2.30#

139.73 ± 3.44#

136.43 ± 3.97

0.000

  Chloine (mmol/L)

103.39 ± 2.66#

103.86 ± 3.06#

100.72 ± 5.07

0.000

  Potassium (mmol/L)

4.19 ± 0.49#

4.16 ± 0.5#

5.10 ± 0.93

0.000

  Bicarbonate (mmol/L)

26.26 ± 2.34#

26.41 ± 2.5#

18.35 ± 4.30

0.000

  Calcium (mmol/L)

2.30 ± 0.09#

2.26 ± 0.10#

2.16 ± 0.22

0.000

  Phosphorus (mmol/L)

1.20 ± 0.22#

1.13 ± 0.22#

2.47 ± 1.10

0.000

  White blood cell (10^9/L)

5.34 ± 1.98

5.45 ± 2.09

5.14 ± 2.59

> 0.05

  Neutrophils (10^9/L)

3.11 ± 1.71#

3.34 ± 1.88*

3.83 ± 2.39

0.004

  Hemoglobin (g/L)

141.66 ± 18.37#

137.65 ± 20.0#

102.59 ± 18.17

0.000

  Lymphocyte (10^9/L)

1.69 ± 0.65#

1.54 ± 0.63#

0.85 ± 0.46

0.000

  Monocyte (10^9/L)

0.45 ± 0.20

0.48 ± 0.25

0.47 ± 0.26

> 0.05

  Platelet (10^9/L)

210.18 ± 58.47#

190.72 ± 57.80#

134.97 ± 52.98

0.000

  1. Group A: eGFR > = 90ml/min/1.73m2, Group B: 15ml/min/1.73m2 < = eGFR < 90ml/min/1.73m2, Group C: Dialysis-dependent patient
  2. CVD: ALT: Alanine aminotransferase, AST Aspartate aminotransferase, CVD Cardiovascular disease, eGFR estimated-Glomerular filtration rate
  3. * : Compared with Group C, P < 0.05; # : Compared with Group C, P < 0.0