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Table 3 Multi-variable cox regression for patient survival patients with diabetes

From: Plasma vaspin levels and clinical outcome in incident peritoneal dialysis patients

 

Univariate analysis

Multivariable analysis

Variable

HR

95%CI

p-value

AHR

95%CI

p-value

Patients with diabetes

Plasma vaspin level quartile

0.975

0.780-1.218

0.820

0.922

0.670-1.268

0.617

Sexa

0.789

0.443-1.404

0.420

   

Age

1.022

0.992-1.053

0.144

   

BMI

0.995

0.932-1.062

0.876

   

CCI

1.179

1.044-1.332

0.008

1.132

0.903-1.420

0.283

SGA

0.564

0.361-0.881

0.012

0.614

0.332-1.172

0.139

MIS

1.079

0.990-1.175

0.083

0.892

0.754-1.054

0.180

Serum albumin

0.936

0.882-0.993

0.029

0.988

0.875-1.116

0.845

HbA1c

1.241

0.940-1.638

0.128

   

LDL

0.950

0.753-1.198

0.664

   

Serum CRP

0.999

0.992-1.007

0.899

   

Total Kt/V

0.869

0.614-1.231

0.430

   

residual GFR

0.942

0.854-1.039

0.229

   

CF_PWV

0.987

0.887-1.098

0.803

   

NPNA

0.373

0.146-0.953

0.039

0.461

0.108-1.967

0.295

MTAC

0.987

0.942-1.035

0.597

   

Overhydration

1.055

0.964-1.154

0.248

   

E: I ratio

4.273

0.872-20.939

0.073

12.088

0.558-261.806

0.112

Adipose tissue mass

1.010

0.991-1.029

0.302

   

Lean tissue mass

0.974

0.950-0.999

0.040

0.988

0.936-1.042

0.650

Serum PTH

1.008

1.000-1.015

0.058

1.008

0.996-1.020

0.173

Serum C-peptide

0.976

0.938-1.016

0.236

   

Patients without diabetes

Variable

HR

95%CI

p-value

AHR

95%CI

p-value

Plasma vaspin level quartile

1.489

0.993-2.232

0.054

2.038

1.191-3.487

0.009

Sexa

1.157

0.486-2.755

0.742

   

Age

1.105

1.056-1.156

<0.001

1.081

0.687-1.703

0.736

BMI

0.995

0.870-1.139

0.945

   

CCI

1.493

1.208-1.844

<0.001

1.169

0.888-1.538

0.265

SGA

0.641

0.238-1.725

0.379

   

MIS

1.148

0.941-1.402

0.174

   

Serum albumin

0.990

0.914-1.073

0.812

   

HbA1c

3.438

1.130-10.462

0.030

5.905

1.302-26.793

0.021

LDL

1.273

0.881-1.839

0.198

   

Serum CRP

0.998

0.985-1.012

0.829

   

Total Kt/V

1.266

0.416-3.859

0.678

   

residual GFR

1.025

0.864-1.215

0.780

   

CF_PWV

1.207

0.960-1.516

0.107

   

NPNA

1.401

0.085-23.078

0.814

   

MTAC

1.044

0.965-1.129

0.285

   

Overhydration

1.091

0.900-1.323

0.374

   

E: I ratio

62.855

1.995-1980.675

0.019

29.769

0.606-1462.659

0.088

Adipose tissue mass

1.019

0.968-1.072

0.473

   

Lean tissue mass

0.979

0.939-1.020

0.312

   

Serum PTH

1.003

1.000-1.005

0.018

1.005

1.002-1.008

<0.001

Serum C-peptide

0.998

0.956-1.042

0.928

   
  1. HR Hazards ratio, AHR Adjusted hazards ratio, CI, Confidence interval, GFR Glomerular filtration rate, CCI Charlson’s comorbidity index, SGA Subjective global assessment overall score, MIS Malnutrition inflammation score, CR_PWV Carotid to radial pulse wave velocity, CF_PWV Carotid to femoral pulse wave velocity, BMI Body mass index, hsCRP High sensitivity C-reactive protein, MTAC Mass transfer areas coefficient of creatinine, NPNA Normalized protein nitrogen appearance, E: I ratio, extra-cellular to intracellular volume ratio, HDL High-density lipoprotein, LDL Low-density lipoprotein, PTH Parathyroid hormone
  2. amale as compared to female
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BMC Nephrology

ISSN: 1471-2369

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