Fig. 1

Trial phase of on-site CKRT dialysate production system. During the testing phase in July 2020, we procured prototypes of 3-D printed biocompatible connectors (A) from a local contractor. Using these connectors along with the IHD machines, dialyzers, and hemodialysis concentrate (B) that we typically use in our adult inpatient dialysis program and sterile bags normally utilized for parenteral nutrition (C), we generated bags of CKRT dialysate to both trial the system and to perform testing for fluid composition and microbiologic contamination. Abbreviations: CKRT, continuous kidney replacement therapy; IHD, intermittent hemodialysis