Table 1 Characteristics of IgAN patients by urinary NAG tertiles at biopsy

No. of patients

213

71

71

71

-

Age, y

41.03 ± 13.33

36.93 ± 10.69

43.89 ± 14.09

42.27 ± 14.08

0.009

Male

118 (55.4%)

43 (60.6%)

43 (60.6%)

32 (45.1%)

0.100

BMI, kg/m²

24.41 ± 4.22

24.75 ± 5.69

24.34 ± 3.22

24.14 ± 3.33

0.683

Hypertension

100 (46.9%)

24 (33.8%)

39 (54.9%)

37 (52.1%)

0.023

Diabetes

9 (4.2%)

3 (4.2%)

2 (2.8%)

4 (5.6%)

0.911

MAP, mmHg

98.77 ± 11.04

97.15 ± 10.61

101.05 ± 11.75

98.09 ± 10.49

0.089

Hemoglobin, g/L

128.59 ± 20.02

131.10 ± 18.94

128.86 ± 20.90

125.82 ± 20.09

0.289

Serum albumin, g/L

39.00 ± 4.68

40.23 ± 4.56

39.41 ± 3.84

37.37 ± 5.14

0.001

CRP, mg/dL

1.65 ± 2.79

1.22 ± 1.65

1.97 ± 3.86

1.78 ± 2.39

0.504

Serum creatinine, mg/dL

1.13 ± 0.53

0.97 ± 0.34

1.19 ± 0.51

1.23 ± 0.66

0.017

eGFR, mL/min/1.73m²

72.85 ± 28.28

84.15 ± 25.10

68.06 ± 28.12

66.34 ± 28.38

< 0.001

Proteinuria, g/24 h

1.48 ± 1.21

1.04 ± 1.02

1.33 ± 0.87

2.07 ± 1.45

< 0.001

Use ACEI/ARBs at biopsy

176 (82.6%)

57 (80.3%)

61 (85.9%)

58(81.7%)

0.654

Oxford MEST-C

 M1

186 (87.3%)

56 (78.9%)

65 (91.5%)

65 (91.5%)

0.032

 E1

32 (15.0%)

8 (11.3%)

11 (15.5%)

13 (18.3%)

0.497

 S1

116 (54.5%)

29 (40.8%)

39 (54.9%)

48 (67.6%)

0.006

 T1-2

101 (47.4%)

24 (33.8%)

37 (52.1%)

40 (56.3%)

0.017

 C1-2

84 (39.4%)

24 (33.8%)

31 (43.7%)

29 (40.8%)

0.465