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Table 1 Clinical and laboratory data of patients with MN

From: The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy

Clinical data

 

pMN

(n = 63)

sMN (n = 24)

P-value

 

Age (years)

55.8 ± 14.3

52.8 ± 14.7

0.388

 

Gender M/F

30/33

6/8

0.087

 

BMI (kg/m2)

31.5 ± 6,3

25.2 ± 4.5

< 0.001

 

SBP (mmHg)

131.4 ± 13.7

124.6 ± 14.8

0.046

 

DBP (mmHg)

82.6 ± 8.5

78.8 ± 11.4

0.095

 

 HR (beat/min)

78.0 ± 10.9

74.0 ± 8.9

0.112

Laboratory data

    
 

Serum creatinine (µmol/l)

104.4 ± 63.3

98.0 ± 92.9

0.714

 

CKD-G1 (number)

23

15

0.030

 

CKD-G2 (number)

16

5

0.658

 

CKD-G3 (number)

18

2

0.050

 

CKD-G4 (number)

5

0

0.316

 

CKD-G5 (number)

1

2

0.183

 

eGFR-EPI (CKD G2-5) (ml/min./1.73 m2)

54.3 ± 20.8

50.8 ± 12.1

0.441

 

serum albumin (g/l)

28.9 ± 7.2

30.0 ± 9.5

0.563

 

serum cholesterol (mmol/l)

8.1 ± 2.8

7.3 ± 3.2

0.256

 

serum trigliceride (mmol/l)

2.8 ± 2.7

2.1 ± 1.1

0.222

 

proteinuria (g/day)

10.1 ± 6.0

5.2 ± 3.7

0.003

 

nephrotic syndrome (number, %)

40 (63.5%)

10 (41.7%)

0.089

 

nephrotic proteinuria without nephrotic syndrome (number, %)

19 (30.2%)

5 (20.8%)

0.435

 

non-nephrotic proteinuria/

nephritic syndrome (number, %)

4 (6.3%)

9 (37.5%)

< 0.001

  1. Values are in mean ± standard deviation (SD) where necessary