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Table 1 Baseline characteristics

From: Clinical covariates influencing clinical outcomes in primary membranous nephropathy

Group

Covariate

Subjects (N)

Valuea

General characteristics

Female sex (N)

74

24.00 (32.43%)

Age (years)

74

59.50 (46.50, 70.00)

follow-up (months)

74

30.50 (7.25, 73.75)

time since diagnosis (biopsy; months)

74

0.00 (0.00, 5.00)

Renal parameters

eGFR (ml/min/1.73m2)

74

55.52 (30.48, 84.09)

UPCR (g/g)

74

5.97 (4.23, 9.27)

Albumin (g/dl)

74

2.85 (2.50, 3.30)

Lipids

Cholesterol (mg/dl)

48

266.75 (230.75, 353.50)

Triglycerides (mg/dl)

41

183.00 (138.00, 277.00)

HDL-Cholesterol (mg/dl)

38

56.00 (46.25, 76.25)

LDL-Cholesterol (mg/dl)

38

173.12 (132.00, 228.25)

ACEI ARB treatment

ACEI/ARB treatment (N)

 

53.00 (71.62%)

ACEI equivalent (Ramipril [mg])

43

10.00 (5.00, 10.00)

ARB equivalent (Candesartan [mg])

16

16.00 (16.00, 40.00)

Immunosuppression

  Prednisone therapy

Prednisone treatment (N)

 

22.00 (29.73%)

Prednisone dose (mg)

22

20.00 (15.00, 34.38)

  Rituximab therapy

Rituximab treatment (N)

 

18.00 (24.32%)

Rituximab dose (mg)

18

1,000.00 (1,000.00, 1,000.00)

  Cyclophosphamide therapy

Cyclophosphamide treatment (N)

 

18.00 (24.32%)

Cyclophosphamide sum dose (mg)

18

2,900.00 (2,041.25, 4,063.75)

  MMF therapy

MMF treatment (N)

 

2.00 (2.70%)

MMF dose (mg)

2

1,500.00 (1,250.00, 1,750.00)

  1. Doses for various administered ACEI and ARB were converted to ramipril or candesartan equivalence dose, respectively
  2. Abbreviations: ACEI Angiotensin converting enzyme inhibitor, ARB Angiotensin-1 receptor blocker, eGFR Estimated glomerular filtration rate, HDL High-density lipoprotein, LDL Low-density lipoprotein, MMF Mycophenolate mofetil, UPCR Urine protein to creatinine ratio
  3. aDiscrete variables: Number, N (%); continuous variables: Median of each variable in the first three months of follow-up (IQR)