Table 2 Clinical characteristics of the final cohort
PTDM (n = 7) | T2DM (n = 6) | NG (n = 4) | p-value PTDM vs T2DM | p-value PTDM vs NG | p-value T2DM vs NG | |
|---|---|---|---|---|---|---|
Sex, Male/Female | 4/3 | 5/1 | 2/2 | |||
Age (years), mean (± SD) | 60,9 (12.3) | 64.3 (12.2) | 53 (5.2) | 0.620 | 0.176 | 0.083 |
Range | 46–76 | 52–81 | 48–58 | |||
BMI (kg/m2), mean (± SD) | 27.2 (1.6) | 30.0 (1.5) | 26.2 (2.2) | 0.007 | 0.413 | 0.010 |
Weight gain post-tx (Kg), mean (± SD) | -2.7 (5.7) | 2.2 (4.6) | 0.25 (0.5) | |||
Fasting glucose-pre-tx (mmol/L), mean (± SD) | 5.3 (0.7) | 11.1 (5.7) | 5.6 (0.3) | 0.051 | 0.277 | 0.065 |
Range | 4.8–6.3 | 4.9–20.7 | 5.4–5.9 | |||
HbA1C test, %, mean (± SD) pre-tx | 5.2 (0.4) | 6.5 (0.7) | 5.3 (0.2) | 0.001 | 0.866 | 0.006 |
Range | 4.5–5.7 | 5.8–7.5 | 5.0–5.5 | |||
HbA1C test, %, mean (± SD) post-tx | 6.7 (0.8) | 7.4 (0.8) | 5.2 (0.2) | 0.123 | 0.008 | < 0.001 |
Range | 5.6–8.0 | 6.5–8.6 | 5.0–5.5 | |||
eGFR (mL/min/1.73 m2), mean (± SD) post-tx | 53 (11) | 39 (8) | 65 (11) | 0.026 | 0.121 | 0.003 |
Hypertension post-tx % | 71 | 100 | 75 | |||
Donor (DD/LD) | 3/4 | 5/1 | 3/1 | |||
Donor age (years), mean (± SD) | 47.8 (15.8) | 64.2 (15.4) | 57.0 (14) | 0.076 | 0.346 | 0.477 |