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Table 4 Risk factors for mortality assessed by univariate and multivariate Cox regression model

From: Impact of initial dialysis modality on the survival of patients with ESRD: a propensity-score-matched study

Variables

Univariate (n = 687)

Multivariate a (n = 687)

PSM b-Multivariate a (n = 250)

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

Sex (female vs. male)

0.67 (0.51–0.89)

0.01

0.64 (0.48–0.86)

<0.01

0.41 (0.23–0.74)

<0.01

Age at dialysis initiation (≥ 65 years)

3.92 (2.99–5.15)

<0.01

2.35 (1.71–3.23)

<0.01

2.56 (1.26–5.18)

0.01

CCI (≥ 5)

4.11 (2.97–5.69)

<0.01

1.77 (1.17–2.68)

0.01

1.20 (0.60–2.39)

0.60

Diabetes

2.46 (1.87–3.23)

<0.01

1.32 (0.89–1.96)

0.16

1.43 (0.69–2.98)

0.34

Cardiovascular disease

1.40 (1.04–1.87)

0.03

1.23 (0.88–1.70)

0.22

0.88 (0.47–1.64)

0.68

Congestive heart failure

2.19 (1.61–2.98)

<0.01

1.77 (1.25–2.51)

<0.01

1.34 (0.54–3.33)

0.53

Cerebrovascular disease

3.16 (2.37–4.22)

<0.01

1.94 (1.42–2.64)

<0.01

2.36 (1.19–4.69)

0.01

Triglyceride (mmol/L)

0.88 (0.78–0.99)

0.04

0.98 (0.86–1.12)

0.81

1.00 (0.81–1.24)

0.99

Plasma albumin (g/L)

0.95 (0.93–0.98)

<0.01

0.98 (0.95–1.01)

0.21

0.98 (0.93–1.04)

0.55

Hemoglobin (g/L)

0.98 (0.97–0.99)

<0.01

0.98 (0.97–0.99)

<0.01

0.97 (0.96–0.98)

<0.01

Dialysis methods (HD vs. PD)

2.06 (1.43–2.97)

<0.01

1.09 (0.73–1.64)

0.68

1.04 (0.61–1.78)

0.89

  1. PSM, Propensity scoring matching; HR, Hazard ratio; 95% CI, 95% confidence interval; CCI, Charlson comorbidities index; HD, Hemodialysis; PD, Peritoneal dialysis
  2. a Variables adjusted in multivariate Cox regression model: Sex, Age at dialysis initiation, CCI, Diabetes, Cardiovascular disease, Congestive heart failure, Cerebrovascular disease, Triglyceride, Plasma albumin, Hemoglobin, Dialysis methods
  3. b The characteristics used in PSM were the same as the variables in the multivariate Cox regression model
  4. Bold values indicate significant statistical differences