From: Vancomycin and daptomycin dosing recommendations in patients receiving home hemodialysis using Monte Carlo simulation
Vancomycin
Daptomycin
Body weight (kg)
93.5 ± 30 [15]
Vd (L/kg)
0.8 ± 0.24 [14, 16]
0.16 ± 0.04 [9, 17,18,19]
Non-renal CL (mL/min)
4 ± 1.2 [14, 16]
3.4 ± 1.3 [9, 17]
Unbound fraction of drug (%)
0.82 ± 0.16 [20]
10–12 [21]
Saturation coefficient
 0.28-0.49 ± 20% [0–1] [14, 16, 22,23,24,25,26,27,28,29,30]
 0.07-0.12 ± 20% [0–1] [17, 19, 31,32,33]
