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Table 3 Albumin fractions before and after haemodialysis treatment

From: Albumin redox state of maintenance haemodialysis patients is positively altered after treatment

 

HMA

HNA-1

HNA-2

All

n = 58

n = 58

n = 58

Before

Treatment*

56.0

50.1–61.2

38.5

33.3–43.2

5.8

5.1–6.7

After

Treatment*

71.6

65.4–76.8

23.2

19.1–28.9

4.8

4.2–5.8

Dialyzer

Material

Polysulfone

n = 48

PMMA

n = 6

CTA

n = 4

Polysulfone

n = 48

PMMA

n = 6

CTA

n = 4

Polysulfone

n = 48

PMMA

n = 6

CTA

n = 4

Before

treatment

55.4

50.0-61.1

59.3

55.4–62.6

57.2

49.5–65.0

38.6

33.1–43.6

35.9

33.3–39.3

37.7

29.7–44.9

6.0

5.3–6.9

4.9

4.1–6.2

5.4

5.0-5.7

After

treatment

70.4

64.8–76.1

76.2

72.1–76.9

79.1

70.2–80.8

25.1

19.8–29.9

19.8

19.0-22.9

16.1

14.9–25.9

4.9

4.3–5.8

4.6

3.6–5.2

4.5

3.8-5.0

Sterilization method

Gamma

n = 20

Inline steam

n = 38

Gamma

n = 20

Inline steam

n = 38

Gamma

n = 20

Inline steam

n = 38

Before

treatment

59.4

56.2–64.6

53.2

49.0-58.6

36.0

30.7–38.9

40.2

34.9–44.1

5.6

4.6–5.9

6.2

5.5–7.3

After

treatment

76.7

73.2–80.3

68.4

62.4–74.3

19.5

15.4–21.0

26.4

20.6–31.2

4.4

3.6–4.8

5.4

4.5–5.9

Ultrafiltration coefficient

High Flux

n = 26

Low Flux

n = 32

High Flux

n = 26

Low Flux

n = 32

High Flux

n = 26

Low Flux

n = 32

Before

Treatment**

59.3

56.3–63.3

51.9

48.9–57.2

35.4

30.9–38.2

41.1

36.8–44.3

5.5

4.5-6.0

6.3

5.6–7.3

After

Treatment**

76.7

73.6–80.4

67.3

61.7–72.6

19.5

15.4–21.4

27.5

22.2–31.7

4.4

3.7–4.9

5.5

4.6-6.0

  1. Table shows albumin fractions according to redox state (%), median and interquartile range (IQR). Abbreviations: HMA human mercaptalbumin, HNA-1 human non-mercaptalbumin 1, HNA-2 human non-mercaptalbumin 2, PMMA polymethylmethacrylate, CTA cellulose triacetate
  2. * Fractions of HMA, HNA-1 and HNA-2 significantly altered after treatment; p < 0.001
  3. ** Fractions of HMA, HNA-1 and HNA-2 significantly differ between high/low flux dialyzers; p < 0.001